Medicinal chemistry of indole derivatives: Current to future therapeutic prospectives

A Kumari, RK Singh - Bioorganic chemistry, 2019 - Elsevier
Indole is a versatile pharmacophore, a privileged scaffold and an outstanding heterocyclic
compound with wide ranges of pharmacological activities due to different mechanisms of …

Medicinal perspective of indole derivatives: recent developments and structure-activity relationship studies

D Kumar, S Sharma, S Kalra, G Singh… - Current drug …, 2020 - ingentaconnect.com
Heterocyclic compounds play a significant role in various biological processes of the human
body and many of them are in clinical use due to their diverse, chemical and biological …

An insight into the medicinal perspective of synthetic analogs of indole: A review

PV Thanikachalam, RK Maurya, V Garg… - European journal of …, 2019 - Elsevier
Heterocycles occupy a salient place in chemistry due to their wide range of activity in the
fields of drug design, photochemistry, agrochemicals, dyes, and so on. Amongst all, indole …

The Multi‐Pharmacological Targeted Role of Indole and its Derivatives: A review

B Suliphuldevara Mathada… - …, 2023 - Wiley Online Library
Heterocycles are a privileged motif that appears as a momentous objective in medicinal
chemistry. An important class of compounds for drug discovery and design is indole and its …

Indoles as therapeutics of interest in medicinal chemistry: Bird's eye view

N Chadha, O Silakari - European Journal of Medicinal Chemistry, 2017 - Elsevier
Indoles constitute extensively explored heterocyclic ring systems with wide range of
applications in pathophysiological conditions that is, cancer, microbial and viral infections …

A brief review of the biological potential of indole derivatives

S Kumar, Ritika - Future Journal of Pharmaceutical Sciences, 2020 - Springer
Background Various bioactive aromatic compounds containing the indole nucleus showed
clinical and biological applications. Indole scaffold has been found in many of the important …

Indoles—A promising scaffold for drug development

TV Sravanthi, SL Manju - European Journal of Pharmaceutical Sciences, 2016 - Elsevier
Generally, heterocycles occupy a prominent place in chemistry due to their wide range of
applications in the fields of drug design, photochemistry, agrochemicals, dyes and so on …

Recent progress in biological activities of indole and indole alkaloids

TP Singh, OM Singh - Mini reviews in medicinal chemistry, 2018 - ingentaconnect.com
The indole scaffold is found in a wide range of bioactive heterocycles and natural products.
Moreover, the indole moiety is considered as the active principle in several alkaloids such …

[PDF][PDF] Indole: the molecule of diverse biological activities

S Biswal, U Sahoo, S Sethy, HKS Kumar… - Asian J. Pharm. Clin …, 2012 - researchgate.net
ABSTRACT A large number of efforts were made to synthesize different heterocyclic
compounds and their derivatives in the past decade and were found to posses promising …

Biomedical importance of indoles

NK Kaushik, N Kaushik, P Attri, N Kumar, CH Kim… - Molecules, 2013 - mdpi.com
The indole nucleus is an important element of many natural and synthetic molecules with
significant biological activity. This review covers some of the relevant and recent …