Transport carriers regulate membrane flow between compartments of the secretory and
endocytic pathways in eukaryotic cells. Carrier biogenesis is assisted by microtubules, actin …

Early in evolution, the diversification of membrane-bound compartments that characterize
eukaryotic cells was accompanied by the elaboration of molecular machineries that mediate …

The endocytic pathway is essential for processes that define how cells interact with their
environment, including receptor signalling, cell adhesion and migration, pathogen entry …

During vesicular transport, the assembly of the coat complexes and the selection of cargo
proteins must be coordinated with the subsequent translocation of vesicles from the donor to …

The cytoskeleton is crucial for the efficient and polarized transport of vesicles in intracellular
membrane-sorting pathways. Recent studies have identified specific kinesin, dynein, and …

The cytoskeleton is essential for the proper function of many components of secretory and
endocytic pathways, and the importance both of microtubule motors (kinesins and dyneins) …

Cytoskeletal motors of the dynein, kinesin and myosin superfamilies maintain and adapt
subcellular organelle organization to meet functional demands and support the vesicular …

Specific subsets of biochemical reactions in eukaryotic cells are restricted to individual
membrane compartments, or organelles. Cells, therefore, face the monumental task of …

Cytoskeleton-associated motor proteins typically drive organelle movements in eukaryotic
cells in a manner that is tightly regulated, both spatially and temporally. In the past year, a …

Protein transport in the secretory and endocytic pathways is a multistep process involving
the generation of transport carriers loaded with defined sets of cargo, the shipment of the …