Methionine is an essential amino acid, involved in the promotion of growth, immunity, and
regulation of energy metabolism. Over the decades, research has long focused on the …

Enhanced oxidative stress is closely related to aging and impaired metabolic health and is
influenced by diet-derived nutrients and energy. Recent studies have shown that methionine …

Methionine restriction (MR) extends lifespan and improves several markers of health in
rodents. However, the proximate mechanisms of MR on these physiological benefits have …

Lifelong dietary methionine restriction (MR) is associated with increased longevity and
decreased incidence of age-related disorders and diseases in rats and mice. A reduction in …

Methionine is one of the essential amino acids and plays a vital role in various cellular
processes. Reports advocate that methionine restriction and supplementation provide …

Restriction of dietary methionine by 80% slows the progression of aged-related diseases
and prolongs lifespan in rodents. A salient feature of the methionine restriction phenotype is …

Methionine restriction (MR) extends lifespan across different species. The main responses of
rodent models to MR are well-documented in adipose tissue (AT) and liver, which have …

Methionine restriction (MetR) extends lifespan across different species and exerts beneficial
effects on metabolic health and inflammatory responses. In contrast, certain cancer cells …

Methionine is an aliphatic, sulfur-containing, essential amino acid, and a precursor of
succinyl-CoA, homocysteine, cysteine, creatine, and carnitine. Recent research has …

Although the effects of dietary methionine restriction have been investigated in the
physiology of aging and diseases related to oxidative stress, the relationship between …