OBJECTIVE: This phase-I study transferred the concept of isovolemic hemodilution, which
has been proven beneficial in the treatment of experimental acute pancreatitis to the patient …

Dextran of different molecular weight (Dx 40, Dx 60/70) has often been evaluated as adjunct
treatment of experimental acute pancreatitis. A beneficial effect has been documented by a …

Much clinical and experimental evidence suggests that pancreatic ischaemia in the early
phase of acute pancreatitis is important in the development of pancreatic necrosis. While …

BACKGROUND: Previous studies demonstrated that intravenous contrast medium (CM), as
used in contrast enhanced computed tomography, aggravates the impairment of pancreatic …

Impairment of the pancreatic microcirculation is a characteristic finding in experimental
biliary pancreatitis. Isovolemic hemodilution with dextran 60 has been proven to maintain …

In spite of extensive investigations, many aspects of the hemodynamic changes occurring in
acute pancreatitis are understood poorly. A dog model was established in which continuous …

Abstract Background/Aims: In previous studies, we have demonstrated that
hemoconcentration was an early marker for necrotizing pancreatitis. The aim of the present …

Restoration and maintenance of intravascular volume is crucial in acute pancreatitis to
prevent hypotension and ensure normal organ perfusion. This study evaluated the …

In this study we evaluated the effects of hydration, oxygenation, peritoneal lavage, and the
protease inhibitor gabexate mesilate in acute hemorrhagic pancreatitis induced by feeding …

Acute pancreatitis is a common inflammatory disorder of the pancreas resulting in
considerable morbidity and a mortality rate of approximately 5%. Although there are no …