Development of an LC-ESI (-)-MS/MS method for the simultaneous quantification of 35 isoprostanes and isofurans derived from the major n3-and n6-PUFAs

KM Rund, AI Ostermann, L Kutzner, JM Galano… - Analytica chimica …, 2018 - Elsevier
Misregulation of oxidative and antioxidative processes in the organism–oxidative stress–
contributes to the pathogenesis of different diseases, eg inflammatory or neurodegenerative …

Assessment of isoprostanes in human plasma: technical considerations and the use of mass spectrometry

YY Lee, JM Galano, C Oger, C Vigor, R Guillaume… - Lipids, 2016 - Springer
Oxygenated lipid mediators released from non-enzymatic peroxidation of polyunsaturated
fatty acids (PUFA) are known to have functional roles in humans. Notably, among these lipid …

Current development in non-enzymatic lipid peroxidation products, isoprostanoids and isofuranoids, in novel biological samples

KS Leung, JM Galano, T Durand, JCY Lee - Free radical research, 2015 - Taylor & Francis
Isoprostanoids and isofuranoids are lipid mediators that can be formed from omega-3 and
omega-6 polyunsaturated fatty acids (PUFAs). F2-isoprostanes formed from arachidonic …

Simultaneous quantitative profiling of 20 isoprostanoids from omega-3 and omega-6 polyunsaturated fatty acids by LC–MS/MS in various biological samples

A Dupuy, P Le Faouder, C Vigor, C Oger… - Analytica Chimica …, 2016 - Elsevier
Isoprostanoids are a group of non-enzymatic oxygenated metabolites of polyunsaturated
fatty acids. It belongs to oxylipins group, which are important lipid mediators in biological …

Non-enzymatic lipid oxidation products in biological systems: assessment of the metabolites from polyunsaturated fatty acids

C Vigor, J Bertrand-Michel, E Pinot, C Oger… - … of Chromatography B, 2014 - Elsevier
Metabolites of non-enzymatic lipid peroxidation of polyunsaturated fatty acids notably
omega-3 and omega-6 fatty acids have become important biomarkers of lipid products …

[HTML][HTML] Classifying oxidative stress by F2-Isoprostane levels in human disease: The re-imagining of a biomarker

GL Milne - Redox biology, 2017 - ncbi.nlm.nih.gov
Oxidative stress as classified by F2-Isoprostanes (F2-IsoPs) in Human Disease: Grab the
Low-Hanging Fruit–The utility of F2-IsoPs as a biomarker of oxidative injury in human …

Moving forward with isoprostanes, neuroprostanes and phytoprostanes: where are we now?

OS Ahmed, JM Galano, T Pavlickova… - Essays in …, 2020 - portlandpress.com
Polyunsaturated fatty acids (PUFAs) are essential components in eukaryotic cell membrane.
They take part in the regulation of cell signalling pathways and act as precursors in …

Isoprostanes and phytoprostanes: bioactive lipids

T Durand, V Bultel-Poncé, A Guy, S El Fangour… - Biochimie, 2011 - Elsevier
Polyunsaturated fatty acids (PUFA) are important constituents in all eukaryotic organisms,
contributing to the structural integrity of biological membranes and serving as precursors for …

Measurement of F2-isoprostanes and isofurans using gas chromatography–mass spectrometry

GL Milne, B Gao, ES Terry, WE Zackert… - Free Radical Biology and …, 2013 - Elsevier
F2-Isoprostanes (IsoPs) are isomers of prostaglandin F2α formed from the nonenzymatic
free radical-catalyzed peroxidation of arachidonic acid. Since discovery of these molecules …

Quantification of 15‐F2t‐isoprostane in human plasma and urine: results from enzyme‐linked immunoassay and liquid chromatography/tandem mass spectrometry …

J Klawitter, M Haschke, T Shokati… - Rapid …, 2011 - Wiley Online Library
Quantification of F2‐isoprostanes is considered a reliable index of the oxidative stress status
in vivo. Several immunoassays and chromatography/mass spectrometry‐based assays are …