Immunity and inflammation in status epilepticus and its sequelae: possibilities for therapeutic application

A Vezzani, R Dingledine… - Expert review of …, 2015 - Taylor & Francis
Status epilepticus (SE) is a life-threatening neurological emergency often refractory to
available treatment options. It is a very heterogeneous condition in terms of clinical …

Neuroimmunology of status epilepticus

A Vezzani, R Di Sapia, V Kebede, S Balosso… - Epilepsy & Behavior, 2023 - Elsevier
Status epilepticus (SE) is a very heterogeneous clinical condition often refractory to
available treatment options. Evidence in animal models shows that neuroinflammation …

[HTML][HTML] Inflammation: a network in the pathogenesis of status epilepticus

M Wang, Y Chen - Frontiers in Molecular Neuroscience, 2018 - frontiersin.org
Status epilepticus (SE) is an abnormally prolonged or recurrent epileptic seizure that is a
serious, life-threatening medical emergency. Notably, it requires prompt and aggressive …

Autoimmunity and inflammation in status epilepticus: from concepts to therapies

FJ Holzer, M Seeck, CM Korff - Expert review of neurotherapeutics, 2014 - Taylor & Francis
The understanding of immunological mechanisms underlying some forms of epilepsy and
encephalitis has rapidly increased for the last 10 years leading to the concept of status …

[HTML][HTML] Neuroinflammation and status epilepticus: a narrative review unraveling a complex interplay

T Foiadelli, A Santangelo, G Costagliola… - Frontiers in …, 2023 - frontiersin.org
Status epilepticus (SE) is a medical emergency resulting from the failure of the mechanisms
involved in seizure termination or from the initiation of pathways involved in abnormally …

Causes of status epilepticus

E Trinka, J Höfler, A Zerbs - Epilepsia, 2012 - Wiley Online Library
Status epilepticus (SE) is the most extreme form of epilepsy. It describes a prolonged seizure
that may occur in patients with previous epilepsy or in acute disorders of the central nervous …

Etiological assessment of status epilepticus

L Valton, M Benaiteau, M Denuelle, F Rulquin… - Revue …, 2020 - Elsevier
Status epilepticus (SE) is a potentially serious condition that can affect vital and functional
prognosis and requires urgent treatment. Etiology is a determining factor in the patient's …

Status epilepticus of inflammatory etiology: a cohort study

M Spatola, J Novy, R Du Pasquier, J Dalmau… - Neurology, 2015 - AAN Enterprises
Objective: Inflammation-related epilepsy is increasingly recognized; however, studies on
status epilepticus (SE) are very infrequent. We therefore aimed to determine the frequency of …

A role for inflammation in status epilepticus is revealed by a review of current therapeutic approaches

D Janigro, PH Iffland II, N Marchi, T Granata - Epilepsia, 2013 - Wiley Online Library
A significant number of patients with epilepsy fail to respond to currently available
antiepileptic drugs. This suggests a need for alternative approaches to reduce the …

Cytokines in new‐onset refractory status epilepticus predict outcomes

A Hanin, J Cespedes, K Dorgham, Y Pulluru… - Annals of …, 2023 - Wiley Online Library
Objective The objective of this study was to investigate inflammation using cerebrospinal
fluid (CSF) and serum cytokines/chemokines in patients with new‐onset refractory status …