A blood transfusion is a common treatment for a range of conditions. Over 112 million blood
transfusions are administered each year worldwide and many patients are thereby exposed …

Background. Prolonged storage of packed red blood cells (PRBCs) may increase morbidity
and mortality, and patients having massive transfusion might be especially susceptible. We …

BACKGROUND Blood transfusion is common in the resuscitation of patients with traumatic
injury. However, the clinical impact of the length of storage of transfused blood is unclear in …

Background: Prior studies have demonstrated that transfusion of older stored blood is
associated with an increased risk of multiple organ failure, infection, and death. These …

Background. Prolonged storage of packed red blood cells (PRBCs) may increase morbidity
and mortality, and patients having massive transfusion might be especially susceptible. We …

Background Randomized, controlled trials have suggested that the transfusion of blood after
prolonged storage does not increase the risk of adverse outcomes among patients, although …

Background Haemorrhage is a common cause of death in trauma patients. Although
transfusions are extensively used in the care of bleeding trauma patients, there is …

When oxygen delivery fails to support aerobic metabolism, a complex state of physiologic
dissonance emerges, broadly designated as shock. As the oxygen debt in shock mounts …

Background: Haemorrhage is a common cause of death in trauma patients. Although
transfusions are extensively used in the care of bleeding trauma patients, there is …

Background The impact of the age of stored red blood cells on mortality in patients
sustaining traumatic injuries requiring transfusion of blood products is unknown. The …