Antigen-specific cytotoxicity by invariant NKT cells in vivo is CD95/CD178-dependent and is correlated with antigenic potency
G Wingender, P Krebs, B Beutler… - The Journal of …, 2010 - journals.aai.org
Invariant NKT (iNKT) cells are a unique subset of T lymphocytes that rapidly carry out
effector functions following activation with glycolipid Ags, such as the model Ag α …
effector functions following activation with glycolipid Ags, such as the model Ag α …
Invariant NKT cells facilitate cytotoxic T-cell activation via direct recognition of CD1d on T cells
Y Qin, S Oh, S Lim, JH Shin, MS Yoon… - Experimental & molecular …, 2019 - nature.com
Invariant natural killer T (iNKT) cells are a major subset of NKT cells that recognize foreign
and endogenous lipid antigens presented by CD1d. Although iNKT cells are …
and endogenous lipid antigens presented by CD1d. Although iNKT cells are …
The In Vivo Response of Invariant Natural Killer T Cells to Glycolipid Antigens
VV Parekh, S Lalani, LV Kaer - International reviews of …, 2007 - Taylor & Francis
Invariant natural killer T (iNKT) cells are a subset of T lymphocytes that recognizes glycolipid
antigens presented by the major histocompatibility complex class I–related protein CD1d …
antigens presented by the major histocompatibility complex class I–related protein CD1d …
Invariant natural killer T cells: innate‐like T cells with potent immunomodulatory activities
L Wu, CL Gabriel, VV Parekh, L Van Kaer - Tissue antigens, 2009 - Wiley Online Library
Invariant natural killer T (iNKT) cells are a subset of T lymphocytes that react with glycolipid
antigens presented by the major histocompatibility complex class I‐related glycoprotein …
antigens presented by the major histocompatibility complex class I‐related glycoprotein …
Impact of bacteria on the phenotype, functions, and therapeutic activities of invariant NKT cells in mice
S Kim, S Lalani, VV Parekh, TL Vincent… - The Journal of …, 2008 - Am Soc Clin Investig
Invariant NKT (iNKT) cells are innate-like lymphocytes that recognize glycolipid antigens in
the context of the MHC class I–like antigen-presenting molecule CD1d. In vivo activation of …
the context of the MHC class I–like antigen-presenting molecule CD1d. In vivo activation of …
Invariant NKT cell anergy is induced by a strong TCR-mediated signal plus co-stimulation
T Iyoda, M Ushida, Y Kimura, K Minamino… - International …, 2010 - academic.oup.com
Vα14 TCR expressing invariant NK T (iNKT) cells recognize α-galactosylceramide
(αGC)/CD1d complex and produce large amounts of various cytokines before the onset of …
(αGC)/CD1d complex and produce large amounts of various cytokines before the onset of …
The regulatory role of invariant NKT cells in tumor immunity
RM McEwen-Smith, M Salio, V Cerundolo - Cancer immunology research, 2015 - AACR
Invariant natural killer T (iNKT) cells are a unique population of T lymphocytes, which lie at
the interface between the innate and adaptive immune systems, and are important …
the interface between the innate and adaptive immune systems, and are important …
α-Galactosylceramide analogs with weak agonist activity for human iNKT cells define new candidate anti-inflammatory agents
G Bricard, MM Venkataswamy, KOA Yu, JS Im… - PloS one, 2010 - journals.plos.org
CD1d-restricted natural killer T cells with invariant T cell receptor α chains (iNKT cells) are a
unique lymphocyte subset that responds to recognition of specific lipid and glycolipid …
unique lymphocyte subset that responds to recognition of specific lipid and glycolipid …
Cutting edge: nonglycosidic CD1d lipid ligands activate human and murine invariant NKT cells
JD Silk, M Salio, BG Reddy, D Shepherd… - The Journal of …, 2008 - journals.aai.org
Invariant NKT cells (iNKT cells) recognize CD1d/glycolipid complexes. We demonstrate that
the nonglycosidic compound threitolceramide efficiently activates iNKT cells, resulting in …
the nonglycosidic compound threitolceramide efficiently activates iNKT cells, resulting in …
IFN-γ-producing human invariant NKT cells promote tumor-associated antigen-specific cytotoxic T cell responses
M Moreno, JW Molling… - The Journal of …, 2008 - journals.aai.org
CD1d-restricted invariant NKT (iNKT) cells can enhance immunity to cancer or prevent
autoimmunity, depending on the cytokine profile secreted. Antitumor effects of the iNKT cell …
autoimmunity, depending on the cytokine profile secreted. Antitumor effects of the iNKT cell …