Cells are fundamental units of life. To ensure the maintenance of homeostasis, integrity of
structural and functional counterparts is needed to be essentially balanced. The …

Cytoskeleton defects, including alterations in microtubule stability, in axonal transport as
well as in actin dynamics, have been characterized in several unrelated neurodegenerative …

Recent observations related to the structure of the cytoskeleton in neurons and novel
cytoskeletal abnormalities involved in the pathophysiology of some neurological diseases …

Oxidative stress is a key mechanism causing protein aggregation, cell death and
neurodegeneration in the nervous system. The neuronal cytoskeleton, that is, microtubules …

Since 2016, when we compiled a very well-received special issue on “Cytoskeletal Proteins
in Health and Neurodegenerative Disease” for Brain Research Bulletin, the field has rapidly …

The neuronal cytoskeleton not only provides the structural backbone of neurons, but also
plays a fundamental role in maintaining neuronal functions. Dysregulation of neuronal …

The cytoskeleton is the major intracellular structure that determines the morphology of
neurons and maintains their structural integrity. It is therefore not surprising that a …

Recently, researches have revealed the key roles of the cytoskeleton in the occurrence and
development of multiple diseases, suggesting that targeting the cytoskeleton is a viable …

The cytoskeleton consists of filamentous protein polymers that form organized structures,
contributing to a multitude of cell life aspects. It includes three types of polymers: the actin …

The cytoskeleton is central to many critical cell processes including those that govern cell
movement, migration, cell division, transport and cell signaling. It is well know that the …