Phthalate exposures and MicroRNA expression in uterine fibroids: the FORGE study

AR Zota, RJ Geller, BN VanNoy… - Epigenetics …, 2020 - journals.sagepub.com
Phthalates are associated with multiple, adverse reproductive outcomes including increased
risk of uterine leiomyoma (fibroids). Phthalates can interact with epigenetic modifications …

[HTML][HTML] Phthalates exposure and uterine fibroid burden among women undergoing surgical treatment for fibroids: a preliminary study

AR Zota, RJ Geller, AM Calafat, CQ Marfori… - Fertility and sterility, 2019 - Elsevier
Objectives To examine the association between phthalate exposure and two measures of
uterine fibroid burden: diameter of largest fibroid and uterine volume. Design Pilot, cross …

[HTML][HTML] Incidence of uterine leiomyoma in relation to urinary concentrations of phthalate and phthalate alternative biomarkers: A prospective ultrasound study

V Fruh, BC Henn, J Weuve, AK Wesselink… - Environment …, 2021 - Elsevier
Background Numerous studies suggest that some phthalates have adverse reproductive
effects. However, literature on the association between phthalates and incidence of uterine …

Association between follicular fluid phthalate concentrations and extracellular vesicle microRNAs expression

Z Barnett-Itzhaki, S Knapp, C Avraham… - Human …, 2021 - academic.oup.com
STUDY QUESTION Are phthalate metabolite concentrations in follicular fluid (FF) associated
with the expression of extracellular vesicle microRNAs (EV-miRNAs)? SUMMARY ANSWER …

Increased urinary phthalate levels in women with uterine leiomyoma: a case-control study

YA Kim, Y Kho, KC Chun, JW Koh, JW Park… - International Journal of …, 2016 - mdpi.com
We assessed the urinary concentration of 16 phthalate metabolites in 57 women with and
without uterine leiomyoma (n= 30 and 27; respectively) to determine the association …

Oxidatively generated DNA damage mediates the associations of exposure to phthalates with uterine fibroids and endometriosis: Findings from TREE cohort

M Zhang, C Liu, XQ Yuan, FP Cui, Y Miao… - Free Radical Biology …, 2023 - Elsevier
Background Epidemiological studies on phthalate exposures in associations with uterine
fibroids (UF) and endometriosis (EMT) are inconsistent. The underlying mechanisms are …

Exposure to organophosphate esters, phthalates, and alternative plasticizers in association with uterine fibroids

G Lee, S Kim, M Bastiaensen, G Malarvannan… - Environmental …, 2020 - Elsevier
Exposure to endocrine disrupting chemicals is suggested to be responsible for the
development or progression of uterine fibroids. However, little is known about risks related to …

Association between urinary phthalate metabolites and risk of breast cancer and uterine leiomyoma

Z Fu, F Zhao, K Chen, J Xu, P Li, D Xia, Y Wu - Reproductive Toxicology, 2017 - Elsevier
Objective The objective of this study was to systematically assess the association between
urinary phthalate metabolites and risk of breast cancer and uterine leiomyoma. Methods …

[HTML][HTML] Endocrine-disrupting chemicals and uterine fibroids

TA Katz, Q Yang, LS Treviño, CL Walker, A Al-Hendy - Fertility and sterility, 2016 - Elsevier
Uterine fibroids are the most frequent gynecologic tumor, affecting 70% to 80% of women
over their lifetime. Although these tumors are benign, they can cause significant morbidity …

Mono-(2-ethyl-5-hydroxyhexyl) phthalate promotes uterine leiomyoma cell survival through tryptophan-kynurenine-AHR pathway activation

T Iizuka, P Yin, A Zuberi, S Kujawa… - Proceedings of the …, 2022 - National Acad Sciences
Uterine leiomyoma is the most common tumor in women and causes severe morbidity in 15
to 30% of reproductive-age women. Epidemiological studies consistently indicate a …