New directions in modelling dysregulated reward seeking for food and drugs

RM Brown, CV Dayas, MH James, RJ Smith - … & Biobehavioral Reviews, 2022 - Elsevier
Behavioral models are central to behavioral neuroscience. To study the neural mechanisms
of maladaptive behaviors (including binge eating and drug addiction), it is essential to …

Low control over palatable food intake in rats is associated with habitual behavior and relapse vulnerability: individual differences

JW de Jong, KE Meijboom, LJMJ Vanderschuren… - PloS one, 2013 - journals.plos.org
The worldwide obesity epidemic poses an enormous and growing threat to public health.
However, the neurobehavioral mechanisms of overeating and obesity are incompletely …

Understanding addiction using animal models

BN Kuhn, PW Kalivas, AC Bobadilla - Frontiers in behavioral …, 2019 - frontiersin.org
Drug addiction is a neuropsychiatric disorder with grave personal consequences that has an
extraordinary global economic impact. Despite decades of research, the options available to …

The drive to eat: comparisons and distinctions between mechanisms of food reward and drug addiction

RJ DiLeone, JR Taylor, MR Picciotto - Nature neuroscience, 2012 - nature.com
The growing rates of obesity have prompted comparisons between the uncontrolled intake
of food and drugs; however, an evaluation of the equivalence of food-and drug-related …

The effect of exposure to drugs on the processing of natural rewards

P Anselme - Neuroscience & Biobehavioral Reviews, 2009 - Elsevier
Why does moderate exposure to a drug reward make natural rewards increasingly attractive
to organisms, whereas prolonged exposure to the same drug reward has the opposite …

[HTML][HTML] Natural and drug rewards engage distinct pathways that converge on coordinated hypothalamic and reward circuits

AL Alhadeff, N Goldstein, O Park, ML Klima, A Vargas… - Neuron, 2019 - cell.com
Motivated behavior is influenced by neural networks that integrate physiological needs.
Here, we describe coordinated regulation of hypothalamic feeding and midbrain reward …

Converging vulnerability factors for compulsive food and drug use

KM Serafine, LE O'Dell, EP Zorrilla - Neuropharmacology, 2021 - Elsevier
Highly palatable foods and substance of abuse have intersecting neurobiological, metabolic
and behavioral effects relevant for understanding vulnerability to conditions related to food …

“Liking” and “wanting” linked to Reward Deficiency Syndrome (RDS): hypothesizing differential responsivity in brain reward circuitry

K Blum, E Gardner, M Oscar-Berman… - Current pharmaceutical …, 2012 - ingentaconnect.com
In an attempt to resolve controversy regarding the causal contributions of mesolimbic
dopamine (DA) systems to reward, we evaluate the three main competing explanatory …

Habitual preference for the nondrug reward in a drug choice setting

Y Vandaele, K Guillem, SH Ahmed - Frontiers in behavioral …, 2020 - frontiersin.org
For adaptive and efficient decision making, it must be possible to select between habitual
alternative courses of action. However, research in rodents suggests that, even in the …

[图书][B] Handbook of reward and decision making

JC Dreher, L Tremblay - 2009 - books.google.com
This book addresses a fundamental question about the nature of behavior: how does the
brain process reward and makes decisions when facing multiple options? The book …