Most of the functions of vitamin A are mediated through the binding of retinoic acid to specific
nuclear receptors that regulate genomic expression. Recent experimental work in transgenic …

Early fetal vitamin A supplies must be regulated to avoid teratogenic consequences from too
little or too much. Late in gestation, adequate maternal vitamin A status is important for …

A still unresolved public health concern is that excessive vitamin A intake, like vitamin A
deficiency, possibly causes birth defects not only in animals but also in man. Due to the low …

Vitamin A deficiency is an endemic nutrition problem throughout much of the developing
world, especially affecting the health and survival of infants, young children, and pregnant …

Advances in molecular biology and retinoic acid receptor research have significantly
contributed to the understanding of the role of vitamin A during vertebrate development …

In 1913, vitamin A was first described as a nutritional factor essential for growth and life itself,
but another 18 years passed before the chemical nature of vitamin A was elucidated (see …

Vitamin A is an essential micronutrient throughout the life cycle. Its active form, retinoic acid
via retinoid receptors, is involved in signal transduction pathways regulating development …

In all populations where vitamin A deficiency is an important public health problem,
prophylactic vitamin A supplements should be given to all infants and young children (0–59 …

Background: Young infants are at risk of vitamin A deficiency. Supplementation of
breastfeeding mothers improves the vitamin A status of their infants, but there are no data …

We examined the relation between the vitamin A status of Spanish women during pregnancy
and concentrations of vitamin A in breast milk. The subjects were 57 healthy, lactating …