Evolving functions of endothelial cells in inflammation

JS Pober, WC Sessa - Nature Reviews Immunology, 2007 - nature.com
Inflammation is usually analysed from the perspective of tissue-infiltrating leukocytes.
Microvascular endothelial cells at a site of inflammation are both active participants in and …

Immune regulation by microvascular endothelial cells: directing innate and adaptive immunity, coagulation, and inflammation

S Danese, E Dejana, C Fiocchi - The Journal of Immunology, 2007 - journals.aai.org
An effective immune response depends not only on the proper activation, regulation, and
function of immune cells, but also on their distribution and retention in diverse tissue …

Cytokine regulation of endothelial cell function: from molecular level to the bedside

A Mantovani, F Bussolino, M Introna - Immunology today, 1997 - cell.com
Endothelial cells (ECs) participate in inflammatory and immune reactions by producing and
responding to cytokines. The molecular basis underlying the functional reprograming of …

[HTML][HTML] Endothelial cells: From innocent bystanders to active participants in immune responses

A Al-Soudi, MH Kaaij, SW Tas - Autoimmunity reviews, 2017 - Elsevier
The endothelium is crucially important for the delivery of oxygen and nutrients throughout
the body under homeostatic conditions. However, it also contributes to pathology, including …

Vascular endothelium and immune responses: implications for inflammation and angiogenesis

Z Szekanecz, AE Koch - Rheumatic Disease Clinics, 2004 - rheumatic.theclinics.com
Endothelial cells (ECs) line the lumina of arteries, veins, and capillaries, thus separating and
connecting the blood and the extravascular tissues. In inflammatory processes (eg, arthritis …

Endothelial cell biology: role in the inflammatory response

M Pate, V Damarla, DS Chi, S Negi… - Advances in clinical …, 2010 - Elsevier
Human endothelial cells are multifunctional cells that line blood vessels and are capable of
secreting a variety of biologically active mediators. They normally maintain vascular …

The endothelium and inflammation

T Trepels, AM Zeiher, S Fichtlscherer - Endothelium, 2006 - Taylor & Francis
The vascular endothelium contributes to and is affected by inflammatory processes.
Disturbance of the endothelium's morphologic and functional integrity in response to …

Endothelial cells

C Sturtzel - The Immunology of Cardiovascular Homeostasis and …, 2017 - Springer
Endothelial cells are a constitutive part of the heart and vasculature and form a crucial link
between the cardiovascular system and the immune system. Besides their commonly …

Heterogeneity in endothelial responsiveness to cytokines, molecular causes, and pharmacological consequences

G Molema - Seminars in thrombosis and hemostasis, 2010 - thieme-connect.com
Microvascular endothelial cells play an essential role in inflammatory diseases. Functional
heterogeneity between microvascular segments in normal organ homeostasis has been …

Role of inflammatory mediators in angiogenesis

A Naldini, F Carraro - Current Drug Targets-Inflammation & …, 2005 - ingentaconnect.com
The angiogenic process involves several cell types and mediators, which interact to
establish a specific microenvironment suitable for the formation of new capillaries from pre …