Myostatin mutation enhances bovine myogenic differentiation through PI3K/AKT/mTOR signalling via removing DNA methylation of RACK1
Y Zhao, X Xia, Q Wang, D Hu, L Zhang, X Li, X Ding… - Cells, 2022 - mdpi.com
Myostatin (MSTN) is a negative regulator of skeletal muscle development and plays an
important role in muscle development. Fluctuations in gene expression influenced by DNA …
important role in muscle development. Fluctuations in gene expression influenced by DNA …
Muscle differentiation induced by p53 signaling pathway-related genes in myostatin-knockout quail myoblasts
JW Park, JH Lee, JS Han, SP Shin, TS Park - Molecular biology reports, 2020 - Springer
The myostatin (MSTN) gene is of interest in the livestock industry because mutations in this
gene are closely related to growth performance and muscle differentiation. Thus, in this …
gene are closely related to growth performance and muscle differentiation. Thus, in this …
Myostatin inactivation induces a similar muscle molecular signature in double-muscled cattle as in mice
I Chelh, B Picard, JF Hocquette, I Cassar-Malek - Animal, 2011 - cambridge.org
Myostatin (MSTN), a member of the TGF-β superfamily, is a negative regulator of skeletal
muscle mass. We have previously shown that the cell survival/apoptosis pathway is a …
muscle mass. We have previously shown that the cell survival/apoptosis pathway is a …
Myostatin knockdown and its effect on myogenic gene expression program in stably transfected goat myoblasts
AK Patel, AK Tripathi, UA Patel, RK Shah… - In Vitro Cellular & …, 2014 - Springer
Myostatin, a negative regulator of skeletal muscle mass, is a proven candidate to modulate
skeletal muscle mass through targeted gene knockdown approach. Here, we report …
skeletal muscle mass through targeted gene knockdown approach. Here, we report …
The critical role of myostatin in differentiation of sheep myoblasts
C Liu, W Li, X Zhang, N Zhang, S He, J Huang… - Biochemical and …, 2012 - Elsevier
Myostatin [MSTN, also known as growth differentiation factor 8 (GDF8)], is an inhibitor of
skeletal muscle growth. Blockade of MSTN function has been reported to result in increased …
skeletal muscle growth. Blockade of MSTN function has been reported to result in increased …
An evolutionarily conserved Myostatin proximal promoter/enhancer confers basal levels of transcription and spatial specificity in vivo
CVC Grade, MS Salerno, FR Schubert… - Development genes and …, 2009 - Springer
Myostatin (Mstn) is a negative regulator of skeletal muscle mass, and Mstn mutations are
responsible for the double muscling phenotype observed in many animal species …
responsible for the double muscling phenotype observed in many animal species …
Down-regulation of Akt/mammalian target of rapamycin signaling pathway in response to myostatin overexpression in skeletal muscle
A Amirouche, AC Durieux, S Banzet… - …, 2009 - academic.oup.com
Myostatin, a member of the TGF-β family, has been identified as a master regulator of
embryonic myogenesis and early postnatal skeletal muscle growth. However, cumulative …
embryonic myogenesis and early postnatal skeletal muscle growth. However, cumulative …
Myostatin regulates fatty acid desaturation and fat deposition through MEF2C/miR222/SCD5 cascade in pigs
H Ren, W Xiao, X Qin, G Cai, H Chen, Z Hua… - Communications …, 2020 - nature.com
Myostatin (MSTN), associated with the “double muscling” phenotype, affects muscle growth
and fat deposition in animals, whereas how MSTN affects adipogenesis remains to be …
and fat deposition in animals, whereas how MSTN affects adipogenesis remains to be …
[HTML][HTML] CARP, a myostatin-downregulated gene in CFM cells, is a novel essential positive regulator of myogenesis
G Ma, H Wang, X Gu, W Li, X Zhang, L Cui… - … journal of biological …, 2014 - ncbi.nlm.nih.gov
Myostatin, a member of the TGF-β superfamily, has been shown to act as a negative
regulator of myogenesis. Although its role in myogenesis has been clearly documented …
regulator of myogenesis. Although its role in myogenesis has been clearly documented …
Regulation of myostatin on the growth and development of skeletal muscle
MM Chen, YP Zhao, Y Zhao, SL Deng… - Frontiers in cell and …, 2021 - frontiersin.org
Myostatin (MSTN), a member of the transforming growth factor-β superfamily, can negatively
regulate the growth and development of skeletal muscle by autocrine or paracrine signaling …
regulate the growth and development of skeletal muscle by autocrine or paracrine signaling …