The voltage-gated KCNQ1 (KvLQT1, Kv7. 1) potassium channel plays a crucial role in
shaping the cardiac action potential as well as in controlling the water and salt homeostasis …

The KCNQ1 channel (also called Kv7. 1 or KvLQT1) belongs to the superfamily of voltage‐
gated K+ (Kv) channels. KCNQ1 shares several general features with other Kv channels but …

Ion channels are essential for basic cellular function and for processes including sensory
perception and intercellular communication in multicellular organisms. Voltage‐gated …

Coexpression of KCNQ2 and KCNQ3 channels results in a 10‐fold increased current
amplitude compared to that of KCNQ2 alone, suggesting the formation of heteromultimeric …

KCNQ4 and KCNQ5 potassium channel subunits are expressed in vascular smooth muscle
cells, although it remains uncertain how these subunits assemble to form functional …

The four known members of the KCND/Kv4 channel family encode voltage-gated potassium
channels. Recent studies provide evidence that members of the Kv4 channel family are …

The KCNQ1 voltage-gated potassium channel and its auxiliary subunit KCNE1 play a crucial
role in the regulation of the heartbeat. The stoichiometry of KCNQ1 and KCNE1 complex has …

KCNQ2 and KCNQ3, both of which are mutated in a type of human neonatal epilepsy, form
heteromeric potassium channels that are expressed in broad regions of the brain. The …

KCNQ1 is a voltage-dependent K+ channel whose gating properties are dramatically altered
by association with auxiliary KCNE proteins. For example, KCNE1, which is mainly …

Potassium channels play an important role in electrical signaling of excitable cells such as
neurons, cardiac myocytes, and vascular smooth muscle cells (VSMCs). In particular, the …