Sucrose induces fatty liver and pancreatic inflammation in male breeder rats independent of excess energy intake

CA Roncal-Jimenez, MA Lanaspa, CJ Rivard… - Metabolism, 2011 - Elsevier
Fructose induces metabolic syndrome in rats; but studies have been criticized for using high
concentrations of fructose that are not physiologic, for using only pure fructose, and for not …

[HTML][HTML] Impact of dietary sucrose on adiposity and glucose homeostasis in C57BL/6J mice depends on mode of ingestion: liquid or solid

J Togo, S Hu, M Li, C Niu, JR Speakman - Molecular metabolism, 2019 - Elsevier
Objective Although it is widely accepted that obesity results from an imbalance of energy
intake and expenditure, the mechanisms underlying this process and effective strategies for …

Differences and similarities in hepatic lipogenesis, gluconeogenesis and oxidative imbalance in mice fed diets rich in fructose or sucrose

A Schultz, S Barbosa-da-Silva, MB Aguila… - Food & function, 2015 - pubs.rsc.org
Changes in feeding habits are the primary environmental factors (though modifiable)
commonly correlated with increase in diseases such as obesity and associated …

Comparison of free fructose and glucose to sucrose in the ability to cause fatty liver

LG Sánchez-Lozada, W Mu, C Roncal… - European journal of …, 2010 - Springer
Background There is evidence that disaccharide sucrose produce a greater increase in
serum fructose and triglycerides (TGs) than the effect produced by their equivalent …

Liquid fructose down-regulates liver insulin receptor substrate 2 and gluconeogenic enzymes by modifying nutrient sensing factors in rats

A Rebollo, N Roglans, M Baena, A Padrosa… - The journal of nutritional …, 2014 - Elsevier
High consumption of fructose-sweetened beverages has been linked to a high prevalence of
chronic metabolic diseases. We have previously shown that a short course of fructose …

Effect of high sucrose feeding on fat accumulation in the male Wistar rat

S Toida, M Takahashi, H Shimizu, N Sato… - Obesity …, 1996 - Wiley Online Library
High sucrose intake is generally thought to be a risk factor for obesity and insulin resistance.
We examined the effects of feeding sucrose on fat accumulation and insulin release in male …

The inflammatory profile and liver damage of a sucrose-rich diet in mice

LSC Oliveira, DA Santos, S Barbosa-da-Silva… - The Journal of nutritional …, 2014 - Elsevier
It is still unclear if an isoenergetic, sucrose-rich diet leads to health consequences. Aims To
investigate the effects of excessive sucrose within an isoenergetic diet on metabolic …

Metabolic and behavioural effects of sucrose and fructose/glucose drinks in the rat

A Sheludiakova, K Rooney, RA Boakes - European journal of nutrition, 2012 - Springer
Purpose Overconsumption of sugar-sweetened beverages, in particular carbonated soft
drinks, promotes the development of overweight and obesity and is associated with …

[HTML][HTML] Fructose induces visceral adipose tissue inflammation and insulin resistance even without development of obesity in adult female but not in male rats

S Kovačević, J Brkljačić, D Vojnović Milutinović… - Frontiers in …, 2021 - frontiersin.org
Introduction: Obesity and related metabolic disturbances are frequently related to modern
lifestyle characterized by excessive fructose intake. Visceral adipose tissue (VAT) …

[HTML][HTML] Early effects of a low fat, fructose-rich diet on liver metabolism, insulin signaling, and oxidative stress in young and adult rats

R Crescenzo, L Cigliano, A Mazzoli… - Frontiers in …, 2018 - frontiersin.org
The increase in the use of refined food, which is rich in fructose, is of particular concern in
children and adolescents, since the total caloric intake and the prevalence of metabolic …