Background: Epithelial ovarian cancer (EOC) cells are prone to metastasise throughout the
peritoneal cavity. The epithelial-to-mesenchymal transition (EMT) is a necessary step …

OBJECTIVES: MUC16 (CA125) protein is a high molecular weight mucin overexpressed in
the majority of epithelial ovarian cancers (EOC) but not in the epithelium of normal ovaries …

The CA125 antigen is found in the serum of many patients with serous ovarian cancer and
has been widely used as a disease marker. CA125 has been shown to be an independent …

Cancer antigen 125 (CA125) is a blood biomarker that is routinely used to monitor the
progression of human epithelial ovarian cancer (EOC) and is encoded by MUC16, a …

Objective Mucin (MUC) 20 has recently been implicated to play a role in human
carcinogenesis. However, the role of MUC20 in epithelial ovarian cancer (EOC) remains to …

After shedding from the primary tumor site, ovarian cancer cells form three-dimensional
multicellular aggregates that serve as vehicle for cancer cell dissemination in the peritoneal …

Background CA125 is a well-established ovarian cancer (OC) serum biomarker. The CA125
heavily glycosylated epitope is carried by the MUC16 mucin, a high molecular weight …

The acquisition of invasiveness in ovarian cancer (OC) is accompanied by the process of
epithelial-to-mesenchymal transition (EMT). The MUC4 mucin is overexpressed in ovarian …

MUC16 (the cancer antigen CA125) is the most commonly used serum biomarker in
epithelial ovarian cancer, with increasing levels reflecting disease progression. It is a …

CA125, the most widely used ovarian cancer biomarker, was first identified approximately 35
years ago in an antibody screen against ovarian cancer antigen. Two decades later, it was …