A series of 3-phenylcoumarins were synthesized and screened for potential antidepressant
activity by tail suspension test (TST) in mice. Three compounds (6, 7 and 13) exhibited …

A new series of coumarin based aminopyran derivatives were designed, synthesized and
evaluated for their preclinical antidepressant effect on Swiss albino mice. Among the series …

Abstract The coumarin-3-cinnamoyl derivatives 2a-d were prepared via Claisen-Schmidt
condensation of 3-acetylcoumarin 1 with different aromatic aldehydes. Cycloaddition …

Abstract Background: Coumarin and 3, 4-dihydroquinolinone nuclei are two heterocyclic
rings that are important and widely exploited for the development of bioactive molecules …

In an effort to develop potent antidepressant agents, new pyrazoline derivatives 2a–s were
synthesized and evaluated for their antidepressant-like activity by tail suspension test (TST) …

Within the scope of our new antidepressant drug development efforts, in this study, we
synthesized eight novel benzothiazole derivatives 3a–3h. The chemical structures of the …

As part of our ongoing studies on the synthesis of bioactive coumarin compounds, we
synthesized a series of new coumarin‐fused 1, 4‐thiazepines using a simple method. The …

In this study, we synthesized a series of 2′, 4′, 6′-trihydroxychalcone derivatives and
evaluated their antidepressant activities. The results of the nine compounds showed …

In this paper, we report the synthesis of novel, potential antipsychotic coumarin derivatives
combining potent dopamine D 2, D 3 and serotonin 5-HT 1A, 5-HT 2A receptors properties …

The discovery and synthesis of potential and novel antipsychotic coumarin derivatives,
associated with potent dopamine D2, D3, and serotonin 5-HT1A and 5-HT2A receptor …