Novel dermal delivery cargos of clobetasol propionate: an update

AB Nair, S Kumar, P Dalal, C Nagpal, S Dalal, R Rao… - Pharmaceutics, 2022 - mdpi.com
Dermal disorders such as psoriasis and eczema are associated with modifications in the
chemical and molecular composition of the skin. Clobetasol propionate (CP), a superpotent …

[HTML][HTML] In vitro skin penetration of clobetasol from lipid nanoparticles: drug extraction and quantitation in different skin layers

LAD Silva, SF Taveira, EM Lima… - Brazilian Journal of …, 2012 - SciELO Brasil
Clobetasol propionate (CP) is a potent topical corticosteroid that causes several cutaneous
and systemic side effects. In the present work, CP was encapsulated in nanostructured lipid …

Nanoencapsulation of clobetasol propionate decreases its penetration to skin layers without changing its relative skin distribution

DF de Andrade, MC Fontana… - … of Nanoscience and …, 2015 - ingentaconnect.com
An immunosuppressive effect with drug release control and higher NTPDase activity in the
treatment of contact dermatitis was previously reported for a hydrogel containing 0.05 …

Biodegradable calcium carbonate carriers for the topical delivery of clobetasol propionate

MS Saveleva, RA Verkhovskii, PA Demina… - Journal of Materials …, 2024 - pubs.rsc.org
Inflammatory dermatoses represent a global problem with increasing prevalence and
recurrence among the world population. Topical glucocorticoids (GCs) are the most …

Nanostructured lipid carriers (NLC) based controlled release topical gel of clobetasol propionate: design and in vivo characterization

U Nagaich, N Gulati - Drug delivery and translational research, 2016 - Springer
Nanostructured lipid carrier (NLC)-based gel was developed as a potential topical system
for clobetasol propionate (CP) topical delivery for the treatment of eczema. The …

Relative efficacy and interchangeability ofvarious clobetasol propionate vehicles in the management of steroid-responsive dermatoses

SR Feldman - Current therapeutic research, 2005 - Elsevier
BACKGROUND:: Topical corticosteroids have long been the cornerstone in thetreatment of
steroid-responsive dermatoses. Despite the effectiveness of these formulations, there is a …

Nanoemulsion loaded gel for topical co-delivery of clobitasol propionate and calcipotriol in psoriasis

A Kaur, SS Katiyar, V Kushwah, S Jain - … : Nanotechnology, biology and …, 2017 - Elsevier
Current work reports the development and optimization of clobitasol propionate (CP) and
calcipotriol (CT) loaded nanoemulsion based gel for topical treatment of psoriasis …

Prolonged skin retention of clobetasol propionate by bio-based microemulsions: A potential tool for scalp psoriasis treatment

R Langasco, ST Tanrıverdi, Ö Özer… - Drug development …, 2018 - Taylor & Francis
Novel effective and cosmetically acceptable formulations are needed for the treatment of
scalp psoriasis, due to the poor efficacy of the current products. The challenge in developing …

Nanocarriers for optimizing the balance between interfollicular permeation and follicular uptake of topically applied clobetasol to minimize adverse effects

C Mathes, A Melero, P Conrad, T Vogt, L Rigo… - Journal of Controlled …, 2016 - Elsevier
The treatment of various hair disorders has become a central focus of good dermatologic
patient care as it affects men and women all over the world. For many inflammatory-based …

Potential use of nanostructured lipid carriers for topical delivery of flurbiprofen

E González-Mira, S Nikolić, ML García, MA Egea… - Journal of …, 2011 - Elsevier
The potential use of nanostructured lipid carriers (NLC) composed of a fatty acid [stearic acid
(SA)] or a triglyceride (glyceryl behenate) as solid lipids, and a mixture of medium chain …