Fluorescence correlations, single molecule detection and large number screening applications in biotechnology
R Rigler - Journal of biotechnology, 1995 - Elsevier
Fluorescence correlation spectroscopy (FCS), when carried out under conditions with low
background as obtained in very small volume elements, is a powerful tool for examining …
background as obtained in very small volume elements, is a powerful tool for examining …
Ultrasensitive investigations of biological systems by fluorescence correlation spectroscopy
E Haustein, P Schwille - Methods, 2003 - Elsevier
Fluorescence correlation spectroscopy (FCS) extracts information about molecular dynamics
from the tiny fluctuations that can be observed in the emission of small ensembles of …
from the tiny fluctuations that can be observed in the emission of small ensembles of …
Analysis of ligand binding by two‐colour fluorescence cross‐correlation spectroscopy
T Weidemann, M Wachsmuth, M Tewes… - Single …, 2002 - Wiley Online Library
Fluorescence correlation spectroscopy (FCS) is a well‐established method for the analysis
of freely diffusing fluorescent particles in solution. In a two‐colour setup, simultaneous …
of freely diffusing fluorescent particles in solution. In a two‐colour setup, simultaneous …
Fluorescence correlation spectroscopy: novel variations of an established technique
E Haustein, P Schwille - Annu. Rev. Biophys. Biomol. Struct., 2007 - annualreviews.org
Fluorescence correlation spectroscopy (FCS) is one of the major biophysical techniques
used for unraveling molecular interactions in vitro and in vivo. It allows minimally invasive …
used for unraveling molecular interactions in vitro and in vivo. It allows minimally invasive …
[PDF][PDF] Fluorescence correlation spectroscopy
P Schwille, E Haustein - A tutorial for the Biophysics Textbook Online …, 2002 - Citeseer
Currently, it is almost impossible to open your daily newspaper without stumbling over words
like gene manipulation, genetic engineering, cloning, etc. that reflect the tremendous impact …
like gene manipulation, genetic engineering, cloning, etc. that reflect the tremendous impact …
Fluorescence correlation spectroscopy for the detection and study of single molecules in biology
MA Medina, P Schwille - Bioessays, 2002 - Wiley Online Library
The recent development of single molecule detection techniques has opened new horizons
for the study of individual macromolecules under physiological conditions. Conformational …
for the study of individual macromolecules under physiological conditions. Conformational …
Recent advances in fluorescence cross-correlation spectroscopy
Fluorescence cross-correlation spectroscopy (FCCS) is a method that measures the
temporal fluorescence fluctuations coming from two differently labeled molecules diffusing …
temporal fluorescence fluctuations coming from two differently labeled molecules diffusing …
Fluorescence correlation spectroscopy: lead discovery by miniaturized HTS
M Auer, KJ Moore, FJ Meyer-Almes, R Guenther… - Drug Discovery …, 1998 - Elsevier
Miniaturized high-throughput screening offers great promise for increasing the productivity of
the pharmaceutical drug discovery process. By monitoring interactions of single molecules …
the pharmaceutical drug discovery process. By monitoring interactions of single molecules …
[HTML][HTML] Recent applications of fluorescence correlation spectroscopy in live systems
R Macháň, T Wohland - FEBS letters, 2014 - Elsevier
Fluorescence correlation spectroscopy (FCS) is a widely used technique in biophysics and
has helped address many questions in the life sciences. It provides important advantages …
has helped address many questions in the life sciences. It provides important advantages …
Recent advances in fluorescence correlation spectroscopy
NL Thompson, AM Lieto, NW Allen - Current opinion in structural biology, 2002 - Elsevier
Fluorescence correlation spectroscopy is a method in which fluctuations in the fluorescence
arising from a very small sample volume are correlated to obtain information about the …
arising from a very small sample volume are correlated to obtain information about the …