Cyclin A1-derived peptides recently gained new interest in a study by Ochsenreither et al.,
who characterized cyclin A1 as a promising antigen in acute myeloid leukemia (AML) due to …

Continuous cell division is a hallmark of cancer and cell-cycle regulators therefore represent
relevant target molecules for tumor therapy. Among these targets the cyclins are of particular …

Cyclin‐A2, a key cell cycle regulator, has been shown to be overexpressed in various types
of malignancies with little expression in normal tissue. Such tumor‐associated genes …

Deregulation of the cell cycle is a key feature of cancer [1, 2] and, therefore, cell cycle
regulators have been suggested as targets for anticancer therapy [3]. The cyclin proteins are …

Purpose: Cyclin D1, a key cell cycle regulator, is overexpressed in multiple types of cancer.
Such tumor-associated genes may be useful targets for cancer immunotherapy …

Uncontrolled cell division is an indispensable event in tumor progression, and numerous
molecules involved in this process have been the focus of intense investigation in tumor …

Cyclin B1, which plays a key role in the control of cell cycle progression from G2 through M
phase, was recently identified by us as a tumor antigen recognized by human T-cells. To …

Cyclin A1 is a promising antigen for T cell therapy being selectively expressed in high-grade
ovarian cancer (OC) and acute myeloid leukemia (AML) stem cells. For adoptive T cell …

We eluted peptides from class I molecules of HLA-A2. 1+ breast adenocarcinoma and
loaded reverse phase high-performance liquid chromatography (HPLC) fractions onto …

Cyclin A is a cell cycle regulatory protein that functions in mitotic and S phase control in
mammalian cells. However, in contrast to other G 1 phase regulatory proteins, such as cyclin …