Parkinson's disease (PD) is an incurable neurodegenerative disease that is rarely
diagnosed at an early stage. Although the understanding of PD-related mechanisms has …

Since diagnosis of Parkinson's disease (PD) is mostly based on clinical criteria, it is almost
impossible to formulate an early diagnosis, as well as a timely differential diagnosis versus …

The discovery of diagnostic and prognostic biomarkers for neurodegenerative diseases
represents an unmet clinical challenge. For example, the diagnosis of Parkinson's disease …

The primary pathogenesis associated with Parkinson's disease (PD) occurs in peripheral
tissues several years before the onset of typical motor symptoms. Early and reliable …

Parkinson's disease (PD) diagnosis is still vulnerable to bias, and a definitive diagnosis
often relies on post-mortem neuropathological diagnosis. In this regard, alpha-synuclein …

Parkinson's disease (PD) is the second most common neurodegenerative disease after
Alzheimer's disease (AD). Although treatments for PD may be beneficial in the early stages …

Abstract Parkinson's disease (PD), the most common neurological motor system disorder,
which characterised by the irreversible loss of dopaminergic neurones in the substantia …

Parkinson's disease (PD) is one of the most common neurodegenerative disorders,
involving progressive loss of the nigro-striatal dopaminergic neurons. Cardinal symptoms …

The discovery of α-synuclein (α-syn) as a major component of Lewy bodies,
neuropathological hallmark of Parkinson's disease (PD), dementia with Lewy bodies and of …

The pursuit of laboratory tests that allow for the reliable and inexpensive identification of
subjects with parkinsonism represents a hot topic in translational neuroscience. This unmet …