Background The widespread occurrence of syphilis remains a global public health problem.
Although penicillin has been recommended as the first-line therapy for syphilis for more than …

Benzathine penicillin G (BPG) is the reference treatment for early syphilis, but shortages
have recently been reported, highlighting a need for the validation of alternative treatments …

Serofast, a persistent nontreponemal serological response observed in early syphilis
patients after conventional treatment, remains a concern of clinicians and syphilis patients …

Background The increasing incidence of syphilis and the limitations of first-line treatment
with penicillin, particularly in neurosyphilis, neonatal syphilis, and pregnancy, highlight the …

Resistance mutations A2058G and A2059G, within the 23S rRNA gene of Treponema
pallidum, have been reported to cause treatment failures in patients receiving azithromycin …

Introduction Syphilis is a globally occurring sexually transmitted disease caused by
Treponema pallidum, a non-cultured in vitro bacterium. Molecular typing of Treponema …

Studies of macrolide resistance mutations and molecular typing using the newly proposed
enhanced typing system for Treponema pallidum isolates obtained from HIV-infected …

Syphilis is a multistage infectious disease that is transmitted sexually by contact with active
lesions of a partner or congenitally from an infected pregnant female to her fetus. Despite …

Background Over the past decade, the incidence of syphilis and widespread macrolide
resistance in its etiological agent, Treponema pallidum subsp. pallidum, have become a …

Syphilis is a multistage infectious disease that is usually transmitted through contact with
active lesions of a sexual partner or from an infected pregnant woman to her fetus. Despite …