ABSTRACT Objectives Human Ficolin-3 (FCN3) is an oligomeric-structured lectin encoded
by the FCN3 gene with a pivotal role in the lectin complement pathway. It has anti-microbial …

Ficolin-3, encoded by the FCN3 gene and expressed in the lung and liver, is a recognition
molecule in the lectin pathway of the complement system. Heterozygosity for an FCN3 …

Abstract Ficolin-3 (also called H-ficolin or Hakata antigen) is the most potent activator of the
lectin pathway of complement in vitro. Its genetically determined deficiency in Caucasians is …

Purpose Ficolin-3 deficiency is caused by a mutation (+ 1637delC) in the FCN3 gene. It is a
rare condition and has been associated with both infection and autoimmune disease …

Ficolins constitute a family of proteins whose biological role has been an enigma for many
years. Over the past few years it has become evident that ficolins are part of the innate …

Background Ficolin-2 coded by FCN2 gene is a soluble serum protein and an innate
immune recognition element of the complement system. FCN2 gene polymorphisms reveal …

Serum H-ficolin (ficolin-3) concentrations (n= 613) and FCN3 genotypes (n= 529) from a
large group of neonates are presented. Both pre-term deliveries and low birthweight …

Ficolin-3 (Hakata antigen or H-ficolin) is a soluble pattern recognition molecule in the lectin
complement pathway. We speculated whether common genetic variations in the FCN3 gene …

We previously reported an association between relative L-ficolin deficiency and recurrent
respiratory infections co-existing with allergic disorders in children. To confirm and extend …

Ficolin-1 is a recognition molecule of the lectin complement pathway. The ficolin-1 gene
FCN1 is polymorphic, but the functional and clinical consequences are unknown. The …