Malaria transmission after artemether-lumefantrine and dihydroartemisinin-piperaquine: a randomized trial

P Sawa, SA Shekalaghe, CJ Drakeley… - The Journal of …, 2013 - academic.oup.com
Background. Artemisinin-based combination therapy (ACT) reduces the potential for malaria
transmission, compared with non-ACTs. It is unclear whether this effect differs between …

[HTML][HTML] Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials

LC Okell, CJ Drakeley, AC Ghani, T Bousema… - Malaria Journal, 2008 - Springer
Background Artemisinin combination therapies (ACT), which are increasingly being
introduced for treatment of Plasmodium falciparum malaria, are more effective against …

Artemether-lumefantrine versus dihydroartemisinin-piperaquine for falciparum malaria: a longitudinal, randomized trial in young Ugandan children

E Arinaitwe, TG Sandison, H Wanzira… - Clinical Infectious …, 2009 - academic.oup.com
Background. Artemisinin-based combination therapies are now widely recommended as first-
line treatment for uncomplicated malaria. However, which therapies are optimal is a matter …

[HTML][HTML] A randomized trial to monitor the efficacy and effectiveness by QT-NASBA of artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment and …

PF Mens, P Sawa, SM van Amsterdam, I Versteeg… - Malaria journal, 2008 - Springer
Background Many countries have implemented artemisinin-based combination therapy
(ACT) for the first-line treatment of malaria. Although many studies have been performed on …

[HTML][HTML] Safety and tolerability of artemether-lumefantrine versus dihydroartemisinin-piperaquine for malaria in young HIV-infected and uninfected children

S Katrak, A Gasasira, E Arinaitwe, A Kakuru, H Wanzira… - Malaria Journal, 2009 - Springer
Background Artemisinin combination therapy has become the standard of care for
uncomplicated malaria in most of Africa. However, there is limited data on the safety and …

Open randomized study of artesunate‐amodiaquine vs. chloroquine‐pyrimethamine‐sulfadoxine for the treatment of uncomplicated Plasmodium falciparum malaria …

A Sowunmi, FA Fehintola, AA Adedeji… - Tropical Medicine & …, 2005 - Wiley Online Library
Background Artemisinin‐based combination antimalarials are currently considered effective
alternatives for the treatment of malaria in Africa, but there are few studies of such …

Residual Plasmodium falciparum Parasitemia in Kenyan Children After Artemisinin-Combination Therapy Is Associated With Increased Transmission to Mosquitoes …

KB Beshir, CJ Sutherland, P Sawa… - The Journal of …, 2013 - academic.oup.com
Background. Parasite clearance time after artemisinin-based combination therapy (ACT)
may be increasing in Asian and African settings. The association between parasite …

The impact of extended treatment with artemether-lumefantrine on antimalarial exposure and reinfection risks in Ugandan children with uncomplicated malaria: a …

ME Whalen, R Kajubi, J Goodwin… - Clinical Infectious …, 2023 - academic.oup.com
Background Artemether-lumefantrine (AL) is the most widely used artemisinin-based
combination therapy in Sub-Saharan Africa and is threatened by the emergence of …

Artesunate Reduces but Does Not Prevent Posttreatment Transmission of Plasmodium falciparum to Anopheles gambiae

G Targett, C Drakeley, M Jawara… - The Journal of …, 2001 - academic.oup.com
Combination therapy that includes artemisinin derivatives cures most falciparum malaria
infections. Lowering transmission by reducing gametocyte infectivity would be an additional …

[HTML][HTML] Artemisinin combination therapies for treatment of uncomplicated malaria in Uganda

H Bukirwa, A Yeka, MR Kamya, A Talisuna… - PLoS clinical …, 2006 - journals.plos.org
Objectives To compare the efficacy and safety of artemisinin combination therapies for the
treatment of uncomplicated falciparum malaria in Uganda. Design Randomized single-blind …