Aging is associated with functional and morphological changes in the sensory organs,
including the auditory system. Mitophagy, a process that regulates the turnover of …

An increase in mitochondrial damage has been associated with a decline in the ability to
mitigate damage through mitophagy in age-related pathologies. The present study aimed to …

Clearance of dysfunctional mitochondria via mitophagy is essential for cell survival and
cochlear functions. However, it is not clear which genes are significantly involved in this …

Mitochondrial dysfunction with aging is associated with the development of age-related
hearing loss. Mitophagy is a cardinal mechanism to maintain a healthy mitochondrial …

Aging of sensory organs is associated with a decline in mitochondrial function and the
accumulation of dysfunctional mitochondria. Impaired mitophagy blocks the turnover of …

Aging is associated with a decline in cognitive function, which can partly be explained by the
accumulation of damage to the brain cells over time. Neurons and glia undergo …

Age-related hearing loss (ARHL), the hearing loss associated with aging, is a vital problem
in present society. The severity of hearing loss is possibly associated with the degeneration …

Presbycusis is the most common sensory impairment associated with aging; however, the
underlying molecular mechanism remains unclear. Autophagy has been demonstrated to …

Alzheimer's disease (AD) is the most common late-onset dementia characterized by the
deposition of extracellular amyloid plaques and formation of intracellular neurofibrillary …

Mitochondrial dysfunction is associated with ototoxicity, which is caused by external factors.
Mitophagy plays a key role in maintaining mitochondrial homeostasis and function and is …