▪ Abstract The past decade has witnessed extraordinary progress in retinal disease gene
identification, the analysis of animal and tissue culture models of disease processes, and the …

The function of the retina is to detect light and to send appropriate signals to the brain in
response. Inherited diseases that cause the retina to degenerate, leading to either partial or …

Diseases of the retina are the leading causes of blindness in the industrialized world. The
recognition that animals develop retinal diseases with similar traits to humans has led to not …

During the last two to three decades, a large body of work has revealed the molecular basis
of many human disorders, including retinal and vitreoretinal degenerations and …

Understanding the influence of gene expression on the molecular mechanisms
underpinning human phenotypic diversity is fundamental to being able to predict health …

One of the great success stories in retinal disease (RD) research in the past decade has
been identification of many of the genes and mutations causing inherited retinal …

Hereditary degenerations and dysfunctions of the retina are an extremely heterogeneous
group of diseases. This summary deals with recent advances in the molecular genetics of a …

Exceptional progress has been made during the past two decades in identifying genes
causing inherited retinal diseases such as retinitis pigmentosa. An inescapable …

The vertebrate retina is comprised of seven major cell types that are generated in
overlapping but well-defined intervals. To identify genes that might regulate retinal …

The introduction of ophthalmoscopy towards the end of the 19th century afforded physicians
for the first time detailed views of the fundus of the eye. Over the subsequent 150 years, a …