Cancer is one of the deadliest diseases worldwide. Recent statistics have shown that
metastases and tumor relapse are the leading causes of cancer‐associated deaths. While …

Cancer is the deadliest disease in the world behind heart disease. Sadly, this remains true
even as we suffer the ravages of the Covid-19 pandemic. Whilst current chemo-and …

Conventional chemotherapeutics, but also innovative precision anticancer compounds, are
commonly perceived to target primarily the cancer cell compartment. However, recently it …

Inducing the immunogenic cell death (ICD) of cancer cells is an important method to improve
the immunogenicity of tumor cells for enhanced cancer immunotherapy. Therefore, we …

The immune system deploys a multitude of innate and adaptive mechanisms not only to
ward off pathogens but also to prevent malignant transformation (“immune surveillance”) …

Immunogenic cell death (ICD) is a rare immunostimulatory form of cell death that can
improve the clinical outcomes of chemo‐immunotherapeutic combination regimens through …

It has been widely thought that the occasional success of anticancer chemotherapies is
mediated by direct, efficient cytostatic or (better) cytotoxic effects of the antineoplastic agent …

Immunogenic cell death (ICD) is a regulated cell death (RCD) pathway. In response to
physical and chemical signals, tumor cells activate specific signaling pathways that stimulate …

Cancer immunotherapy has been acknowledged as a new paradigm for cancer treatment,
with notable therapeutic effects on certain cancer types. Despite their significant potential …

More than 120 years ago William Coley first tested the concept of manipulating the immune
system to fight cancer by using bacterial products to treat patients with solid tumors.[1] Low …