Background Muscle weakness is a complication of critical illness which hampers recovery.
In critically ill mice, supplementation with the ketone body 3-hydroxybutyrate has been …

Background ICU-acquired weakness is a debilitating consequence of prolonged critical
illness that is associated with poor outcome. Recently, premorbid obesity has been shown to …

Background Intensive care unit acquired weakness is a serious problem, contributing to
respiratory failure and reductions in ambulation. Currently, there is no pharmacological …

Introduction Our primary objective was to determine the impact of traumatic injury, onset of
infection, organ/metabolic dysfunction, and mortality on serum cholesterol. Methods During …

Background Recent evidence suggests a potentially protective effect of increasing ketone
body availability via accepting low macronutrient intake early after onset of critical illness …

Background Intensive care unit-acquired weakness (ICU-AW) is a prevalent and severe
issue among ICU patients. Resistance training and beta-hydroxy-beta-methylbutyrate (HMB) …

Methods Nine critically ill patients (58.75±25 to 75 years old) with an ICU stay from 1 day to
5 weeks were evaluated for skeletal muscle glycogen content using a rapid, non-invasive …

Introduction ICU-acquired muscle weakness commonly occurs in patients with septic shock
and is associated with poor outcome. Although atrophy is known to be involved, it is unclear …

Background A defining feature of prolonged critical illness is muscle wasting, leading to
impaired recovery. Supplementation with a tailored blend of amino acids may bolster the …

Introduction Pronounced extracellular acidosis reduces both cardiac contractility and the β-
adrenergic response. In the past, this was shown in some studies using animal models …