Combination of cell-penetrating peptides with nanoparticles for therapeutic application: a review
Cell-penetrating peptides (CPPs), also known as protein translocation domains, membrane
translocating sequences or Trojan peptides, are small molecules of 6 to 30 amino acid …
translocating sequences or Trojan peptides, are small molecules of 6 to 30 amino acid …
[HTML][HTML] Cell-penetrating peptides—a brief introduction
The ability to translocate the cellular membranes and gain access to the cell interior,
including the different cellular compartments, still remains a major obstacle in current drug …
including the different cellular compartments, still remains a major obstacle in current drug …
Cell penetrating peptides: the potent multi-cargo intracellular carriers
ABSTRACT Introduction: Cell penetrating peptides (CPPs) known as protein translocation
domains (PTD), membrane translocating sequences (MTS), or Trojan peptides (TP) are able …
domains (PTD), membrane translocating sequences (MTS), or Trojan peptides (TP) are able …
A survey on “Trojan Horse” peptides: opportunities, issues and controlled entry to “Troy”
NQ Shi, XR Qi, B Xiang, Y Zhang - Journal of controlled release, 2014 - Elsevier
Abstract Cell-penetrating peptides (CPPs), often vividly termed as the “Trojan Horse”
peptides, have attracted considerable interest for the intracellular delivery of a wide range of …
peptides, have attracted considerable interest for the intracellular delivery of a wide range of …
1988–2018: Thirty years of drug smuggling at the nano scale. Challenges and opportunities of cell-penetrating peptides in biomedical research
In 1988, two unrelated papers reported the discovery of peptide vectors with innate cell
translocation properties, setting the ground for a new area of research that over the years …
translocation properties, setting the ground for a new area of research that over the years …
[HTML][HTML] Cell penetrating peptides: A concise review with emphasis on biomedical applications
H Derakhshankhah, S Jafari - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Introduction The biological membranes as natural permeable barriers are required for
survival and function of living cells. However, these natural barriers could be a major …
survival and function of living cells. However, these natural barriers could be a major …
[HTML][HTML] Potential of cell-penetrating peptides (CPPs) in delivery of antiviral therapeutics and vaccines
Viral infections are a great threat to human health. Currently, there are no effective vaccines
and antiviral drugs against the majority of viral diseases, suggesting the need to develop …
and antiviral drugs against the majority of viral diseases, suggesting the need to develop …
Cell-penetrating peptides with intracellular organelle targeting
Introduction: One of the major limiting steps in order to have an effective drug is the passage
through one or more cell membranes to reach its site of action. To reach the action-site, the …
through one or more cell membranes to reach its site of action. To reach the action-site, the …
Intracellular delivery of molecular cargo using cell-penetrating peptides and the combination strategies
H Li, TY Tsui, W Ma - International journal of molecular sciences, 2015 - mdpi.com
Cell-penetrating peptides (CPPs) can cross cellular membranes in a non-toxic fashion,
improving the intracellular delivery of various molecular cargos such as nanoparticles, small …
improving the intracellular delivery of various molecular cargos such as nanoparticles, small …
Intelligent substance delivery into cells using cell-penetrating peptides
T Tashima - Bioorganic & Medicinal Chemistry Letters, 2017 - Elsevier
Cell-penetrating peptides (CPPs) are oligopeptides that can permeate the cell membrane.
The use of a CPP-mediated transport system could be an excellent method for delivering …
The use of a CPP-mediated transport system could be an excellent method for delivering …