North America is in the midst of a major shift in demographics. The mean age of the
population is increasing significantly, and the fastest growth is in the age group of 65 years …

Previous studies using pulsed Doppler echocardiography have demonstrated a pattern of
abnormal left ventricular relaxation associated with increasing age. Specifically, aging is …

OBJECTIVE: To review the incidence, pathophysiology, significance, diagnosis, and
treatment of heart failure with normal systolic function in older patients DATA SOURCE …

About 50% of patients in the older age range who have heart failure have normal systolic
function. There have been several major barriers to understanding the pathophysiology and …

Most elderly patients, particularly women, who have heart failure have a normal ejection
fraction. Patients who have this syndrome have severe symptoms of exercise intolerance …

It is now clear that diastolic heart failure (DHF) is an important, perhaps even dominant form
of heart failure in older Americans. However, our knowledge base regarding the …

In an aging society with persistent high prevalence of cardiovascular disease (CVD) in the
elderly population, the health care system is facing an increasing challenge to effectively …

The number of older individuals, and the proportion that they represent of the total
population, are rapidly increasing. Even more striking is the high proportion the elderly …

Studies have demonstrated that diastolic dysfunction is frequently present in asymptomatic
community-based individuals, especially in the elderly with hypertension, coronary artery …

It is difficult to differentiate the normal ageing process from age-related pathology especially
in relation to effects on the cardiovascular system of humans. The difference between the …