Cancer stem cells (CSCs), known also as tumor-initiating cells, are quiescent, pluripotent,
self-renewing neoplastic cells that were first identified in hematologic tumors and soon after …

Glioblastoma multiforme (GBM) is among the most incurable cancers. GBMs survival rate
has not markedly improved, despite new radical surgery protocols, the introduction of new …

Glioma stem cells (GSCs) constitute a slow-dividing, small population within a
heterogeneous glioblastoma. They are able to self-renew, recapitulate a whole tumor, and …

Glioblastoma is the most common and lethal type of primary brain tumor. Despite recent
therapeutic advances in other cancers, the treatment of glioblastomas remains ineffective …

Glioblastoma ranks among the most lethal of all human cancers. Glioblastomas display
striking cellular heterogeneity, with stem-like glioblastoma stem cells (GSCs) at the apex …

Glioblastoma (GBM) is known to be the most common and lethal primary malignant brain
tumor. Therapies against this neoplasia have a high percentage of failure, associated with …

Glioblastoma is the most common and most aggressive primary brain malignancy. The
current initial standard of care consists of maximal safe surgical resection followed by radical …

Simple Summary Glioblastoma is among the most lethal cancers in humans. Glioblastomas
exhibit a striking heterogeneity, which is maintained by a highly plastic, adaptable …

Recurrence in glioblastoma is nearly universal, and its prognosis remains dismal despite
significant advances in treatment over the past decade. Glioblastoma demonstrates …

Glioblastomas (GBMs) are highly lethal primary brain tumors. Despite current therapeutic
advances in other solid cancers, the treatment of these malignant gliomas remains …