Hyphenated LC–MALDI–ToF/ToF and LC–ESI–QToF approach in proteomic characterization of honeybee venom

J Matysiak, J Hajduk, F Mayer, R Hebeler… - … of Pharmaceutical and …, 2016 - Elsevier
To increase in the depth characterization of venom proteome of Apis mellifera the
hyphenated LC–MALDI–ToF/ToF–MS (liquid chromatography–matrix-assisted laser …

Characterization of honeybee venom by MALDI-TOF and nanoESI-QqTOF mass spectrometry

J Matysiak, CEH Schmelzer, RHH Neubert… - … of Pharmaceutical and …, 2011 - Elsevier
The aim of the study was to comprehensively characterize different honeybee venom
samples applying two complementary mass spectrometry methods. 41 honeybee venom …

Shotgun proteome analysis of honeybee venom using targeted enrichment strategies

J Matysiak, J Hajduk, Ł Pietrzak, CEH Schmelzer… - Toxicon, 2014 - Elsevier
The aim of this study was to explore the honeybee venom proteome applying a shotgun
proteomics approach using different enrichment strategies (combinatorial peptide ligand …

Exploring the hidden honeybee (Apis mellifera) venom proteome by integrating a combinatorial peptide ligand library approach with FTMS

M Van Vaerenbergh, G Debyser, B Devreese… - Journal of …, 2014 - Elsevier
At present, 30 compounds have been described in the venom of the honeybee, and 16 of
them were confirmed by mass spectrometry. Previous studies typically combined 2-D PAGE …

[PDF][PDF] Exploring Apis mellifera venom compounds using highly efficient methods

RE Ionete, OR Dinca, R Tamaian… - Smart Energy and …, 2013 - energ-en.ro
The aim of this study was to develop an accurate and efficient technique based on combined
chromatographic and mass-spectrometry methods for simultaneous determination and …

[HTML][HTML] Proteome and phosphoproteome analysis of honeybee (Apis mellifera) venom collected from electrical stimulation and manual extraction of the venom gland

R Li, L Zhang, Y Fang, B Han, X Lu, T Zhou, M Feng… - BMC genomics, 2013 - Springer
Background Honeybee venom is a complicated defensive toxin that has a wide range of
pharmacologically active compounds. Some of these compounds are useful for human …

[HTML][HTML] Honeybee venom proteome profile of queens and winter bees as determined by a mass spectrometric approach

EL Danneels, M Van Vaerenbergh, G Debyser… - Toxins, 2015 - mdpi.com
Venoms of invertebrates contain an enormous diversity of proteins, peptides, and other
classes of substances. Insect venoms are characterized by a large interspecific variation …

[HTML][HTML] First Characterization of The Venom from Apis mellifera syriaca, A Honeybee from The Middle East Region

J Frangieh, Y Salma, K Haddad, C Mattei, C Legros… - Toxins, 2019 - mdpi.com
Bee venom is a mixture of several components with proven therapeutic benefits, among
which are anti-inflammatory, analgesic, and various cardiovascular conditions. In this work …

[HTML][HTML] Influence of honeybee sting on peptidome profile in human serum

J Matysiak, A Światły, J Hajduk, J Matysiak, ZJ Kokot - Toxins, 2015 - mdpi.com
The aim of this study was to explore the serum peptide profiles from honeybee stung and
non-stung individuals. Two groups of serum samples obtained from 27 beekeepers were …

[HTML][HTML] Proteomic features characterization of Hymenoptera venom allergy

E Matuszewska, J Matysiak, A Bręborowicz… - Allergy, Asthma & …, 2019 - Springer
Background Hymenoptera venom allergy is one of the most frequent causes of anaphylaxis.
In its most severe form, the reaction to wasp and honey bee stings may be life-threatening …