[HTML][HTML] Data, reagents, assays and merits of proteomics for SARS-CoV-2 research and testing

J Zecha, CY Lee, FP Bayer, C Meng, V Grass… - Molecular & Cellular …, 2020 - ASBMB
As the COVID-19 pandemic continues to spread, thousands of scientists around the globe
have changed research direction to understand better how the virus works and to find out …

Proteomics and informatics for understanding phases and identifying biomarkers in COVID-19 disease

AD Whetton, GW Preston, S Abubeker… - Journal of proteome …, 2020 - ACS Publications
The emergence of novel coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2
coronavirus, has necessitated the urgent development of new diagnostic and therapeutic …

[HTML][HTML] Targeted proteomics as a tool to detect SARS-CoV-2 proteins in clinical specimens

K Bezstarosti, MM Lamers, WAS Doff, PC Wever… - PLoS …, 2021 - journals.plos.org
The rapid, sensitive and specific detection of SARS-CoV-2 is critical in responding to the
current COVID-19 outbreak. In this proof-of-concept study, we explored the potential of …

Proteomic approaches to study SARS-CoV-2 biology and COVID-19 pathology

P Haas, M Muralidharan, NJ Krogan… - Journal of proteome …, 2021 - ACS Publications
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative
agent of coronavirus disease 2019 (COVID-19), was declared a pandemic infection in March …

Quantitative assessment of SARS-CoV-2 virus in nasopharyngeal swabs stored in transport medium by a straightforward LC-MS/MS assay targeting nucleocapsid …

J Saadi, S Oueslati, L Bellanger, F Gallais… - Journal of Proteome …, 2021 - ACS Publications
Alternative methods to RT-PCR for SARS-CoV-2 detection are investigated to provide
complementary data on viral proteins, increase the number of tests performed, or identify …

Cov-MS: a community-based template assay for mass-spectrometry-based protein detection in SARS-CoV-2 patients

B Van Puyvelde, K Van Uytfanghe, O Tytgat… - Jacs Au, 2021 - ACS Publications
Rising population density and global mobility are among the reasons why pathogens such
as SARS-CoV-2, the virus that causes COVID-19, spread so rapidly across the globe. The …

[HTML][HTML] Establishing a mass spectrometry-based system for rapid detection of SARS-CoV-2 in large clinical sample cohorts

KHM Cardozo, A Lebkuchen, GG Okai… - Nature …, 2020 - nature.com
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is pressing
public health systems around the world, and large population testing is a key step to control …

Discovery proteomics for COVID-19: where we are now

A McArdle, KE Washington… - Journal of proteome …, 2021 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
coronavirus responsible for the pandemic coronavirus disease 2019 (COVID-19), which has …

Rapid and sensitive detection of SARS-CoV-2 infection using quantitative peptide enrichment LC-MS analysis

A Hober, KH Tran-Minh, D Foley, T McDonald… - Elife, 2021 - elifesciences.org
Reliable, robust, large-scale molecular testing for SARS-CoV-2 is essential for monitoring
the ongoing Covid-19 pandemic. We have developed a scalable analytical approach to …

Proteotyping SARS-CoV-2 virus from nasopharyngeal swabs: a proof-of-concept focused on a 3 min mass spectrometry window

D Gouveia, G Miotello, F Gallais… - Journal of Proteome …, 2020 - ACS Publications
Rapid but yet sensitive, specific, and high-throughput detection of the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) in clinical samples is key to diagnose …