A Novel Method to Repair Thin Endometrium and Restore Fertility Based on Menstruation-Derived Stem Cell

K Chen, H Wang, X Zhao, J Wang, Q Jin, X Tong… - Reproductive …, 2024 - Springer
Thin endometrium (TE), which mainly occurs as a result of severe damage to the
endometrial basalis, is one of the prominent etiologies of menstrual abnormalities, infertility …

[HTML][HTML] Human menstrual blood-derived mesenchymal stem cells regulation of the EGF/Ras p21 pathway as a potential therapeutic target for thin endometrium

M Zhao, F Chi, T Zhang, X Teng, K Li - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
Background Human infertility is caused by many factors, among which thin endometrium is
the main reason for poor embryo implantation. Currently, stem cell therapy could be a …

Mesenchymal stem cells for restoring endometrial function: An infertility perspective

R Rungsiwiwut, P Virutamasen… - … Medicine and Biology, 2021 - Wiley Online Library
Abstract Background Mesenchymal stem cells (MSCs) can be derived from several tissues
such as bone marrow, placenta, adipose tissue, or endometrial tissue. MSCs gain a lot of …

Impaired receptivity of thin endometrium: therapeutic potential of mesenchymal stem cells

MH Saad-Naguib, Y Kenfack, LS Sherman… - Frontiers in …, 2024 - frontiersin.org
The endometrium is a resilient and highly dynamic tissue, undergoing cyclic renewal in
preparation for embryo implantation. Cyclic endometrial regeneration depends on the intact …

Mesenchymal stem cell secretome alters gene expression and upregulates motility of human endometrial stromal cells

Q Zhao, K Larios, Y Naaldijk, LS Sherman… - …, 2023 - rep.bioscientifica.com
In brief Endometrial stromal cell motility is fundamental to regeneration and repair of this
tissue and crucial for successful reproduction. This paper shows a role for the mesenchymal …

Novel therapeutic strategies for injured endometrium: intrauterine transplantation of menstrual blood‑derived cells from infertile patients

S Hosoya, R Yokomizo, H Kishigami, Y Fujiki… - Stem Cell Research & …, 2023 - Springer
Background Menstrual blood-derived cells show regenerative potential as a mesenchymal
stem cell and may therefore be a novel stem cell source of treatment for refractory infertility …

[HTML][HTML] Human endometrium-derived mesenchymal stem/stromal cells application in endometrial-factor induced infertility

R Bausyte, B Vaigauskaite-Mazeikiene… - Frontiers in cell and …, 2023 - ncbi.nlm.nih.gov
Endometrial-factor induced infertility remains one of the most significant pathology among all
fertility disorders. Stem cell-based therapy is considered to be the next-generation approach …

Bone Marrow-and Umbilical Cord-Derived Mesenchymal Stem Cell Secretome Alters Gene Expression and Upregulates Motility of Human Endometrial Stromal Cells

Q Zhao, K Larios, Y Naaldijk, L Sherman… - bioRxiv, 2022 - biorxiv.org
Introduction Cyclic regeneration of the endometrium, and its repair after parturition or injury,
are crucial for successful reproduction. Mesenchymal stem cells (MSCs) derived from bone …

Novel therapeutic strategies for injured endometrium: Autologous intrauterine transplantation of menstrual blood-derived cells from infertile patients

S Hosoya, R Yokomizo, H Kishigami, Y Fujiki… - bioRxiv, 2022 - biorxiv.org
Background Menstrual blood-derived cells show regenerative potential as a mesenchymal
stem cell and may therefore be a novel stem cell source of treatment for refractory infertility …

Effects of menstrual blood‑derived stem cells on endometrial injury repair

J Hu, K Song, J Zhang, Y Zhang… - Molecular medicine …, 2019 - spandidos-publications.com
The present study aimed to investigate the effects of menstrual blood‑derived stem cells
(MenSCs) on endometrial injury repair. MenSCs were isolated from human menstrual blood …