[HTML][HTML] Mechanistic role of HPV-associated early proteins in cervical cancer: Molecular pathways and targeted therapeutic strategies

R Bhattacharjee, SS Das, SS Biswal, A Nath… - Critical reviews in …, 2022 - Elsevier
Purpose Cervical cancer (CC), one of the major causes of death of women throughout the
world is primarily caused due to Human Papilloma Virus (HPV) 16 and 18. The early region …

HPV: Molecular pathways and targets

S Gupta, P Kumar, BC Das - Current problems in cancer, 2018 - Elsevier
Infection of high-risk human papillomaviruses (HPVs) is a prerequisite for the development
of cervical carcinoma. HPV infections are also implicated in the development of other types …

Human papillomavirus E6 and E7: the cervical cancer hallmarks and targets for therapy

A Pal, R Kundu - Frontiers in microbiology, 2020 - frontiersin.org
Human papillomavirus (HPV)-induced cervical cancer is a major health issue among
women from the poorly/under-developed sectors of the world. It accounts for a high-mortality …

Molecular targets of HPV oncoproteins: potential biomarkers for cervical carcinogenesis

AC de Freitas, EC Coimbra, MCG Leitão - Biochimica et Biophysica Acta …, 2014 - Elsevier
Cervical cancer is the second most common cancer among women worldwide and is
responsible for 275,000 deaths each year. Persistent infection with high-risk human …

Human papillomavirus type 16 E5 oncoprotein as a new target for cervical cancer treatment

MK Kim, HS Kim, SH Kim, JM Oh, JY Han… - Biochemical …, 2010 - Elsevier
Human papillomavirus (HPV) infection is considered to be the necessary cause of cervical
cancer. E6 and E7 oncoproteins of HPV have been known to play major roles in malignant …

HPV E6/E7: insights into their regulatory role and mechanism in signaling pathways in HPV-associated tumor

Q Peng, L Wang, L Zuo, S Gao, X Jiang, Y Han… - Cancer gene …, 2024 - nature.com
Human papillomavirus (HPV) is a class of envelope-free double-stranded DNA virus. HPV
infection has been strongly associated with the development of many malignancies, such as …

[HTML][HTML] The role of HPV E6 and E7 oncoproteins in HPV-associated cervical carcinogenesis

EK Yim, JS Park - … research and treatment: official journal of …, 2005 - synapse.koreamed.org
Cervical cancer is one of the leading world causes of cancer morbidity and mortality in
woman, with more than 98% related to a human papillomavirus (HPV) infection origin …

Molecular mechanisms of human papillomavirus-induced carcinogenesis

M Lehoux, CM D'Abramo, J Archambault - Public health genomics, 2009 - karger.com
Approximately 20% of all cancers are associated with infectious agents. Among them,
human papillomaviruses (HPVs) are very common and are now recognized as the …

E6-mediated activation of JNK drives EGFR signalling to promote proliferation and viral oncoprotein expression in cervical cancer

EL Morgan, JA Scarth, MR Patterson… - Cell Death & …, 2021 - nature.com
Human papillomaviruses (HPV) are a major cause of malignancy worldwide, contributing
to~ 5% of all human cancers including almost all cases of cervical cancer and a growing …

RETRACTED ARTICLE: Molecular mechanisms in progression of HPV-associated cervical carcinogenesis

SM Gupta, J Mania-Pramanik - Journal of biomedical science, 2019 - Springer
Cervical cancer is the fourth most frequent cancer in women worldwide and a major cause of
mortality in developing countries. Persistent infection with high-risk human papillomavirus …