Differential innervation of direct-and indirect-pathway striatal projection neurons
The striatum integrates information from multiple brain regions to shape motor learning. The
two major projection cell types in striatum target different downstream basal ganglia targets …
two major projection cell types in striatum target different downstream basal ganglia targets …
The respective activation and silencing of striatal direct and indirect pathway neurons support behavior encoding
C Varin, A Cornil, D Houtteman, P Bonnavion… - Nature …, 2023 - nature.com
The basal ganglia are known to control actions and modulate movements. Neuronal activity
in the two efferent pathways of the dorsal striatum is critical for appropriate behavioral …
in the two efferent pathways of the dorsal striatum is critical for appropriate behavioral …
Control of basal ganglia output by direct and indirect pathway projection neurons
BS Freeze, AV Kravitz, N Hammack… - Journal of …, 2013 - Soc Neuroscience
The direct and indirect efferent pathways from striatum ultimately reconverge to influence
basal ganglia output nuclei, which in turn regulate behavior via thalamocortical and …
basal ganglia output nuclei, which in turn regulate behavior via thalamocortical and …
Whole-brain mapping of inputs to projection neurons and cholinergic interneurons in the dorsal striatum
The dorsal striatum integrates inputs from multiple brain areas to coordinate voluntary
movements, associative plasticity, and reinforcement learning. Its projection neurons consist …
movements, associative plasticity, and reinforcement learning. Its projection neurons consist …
Functional roles of neurotransmitters and neuromodulators in the dorsal striatum
The dorsal striatum, with its functional microcircuits galore, serves as the primary gateway of
the basal ganglia and is known to play a key role in implicit learning. Initially, excitatory …
the basal ganglia and is known to play a key role in implicit learning. Initially, excitatory …
Distinct roles for motor cortical and thalamic inputs to striatum during motor skill learning and execution
SBE Wolff, R Ko, BP Ölveczky - Science advances, 2022 - science.org
The acquisition and execution of motor skills are mediated by a distributed motor network,
spanning cortical and subcortical brain areas. The sensorimotor striatum is an important cog …
spanning cortical and subcortical brain areas. The sensorimotor striatum is an important cog …
Striatal plasticity and basal ganglia circuit function
AC Kreitzer, RC Malenka - Neuron, 2008 - cell.com
The dorsal striatum, which consists of the caudate and putamen, is the gateway to the basal
ganglia. It receives convergent excitatory afferents from cortex and thalamus and forms the …
ganglia. It receives convergent excitatory afferents from cortex and thalamus and forms the …
Opponent control of behavior by dorsomedial striatal pathways depends on task demands and internal state
A classic view of the striatum holds that activity in direct and indirect pathways oppositely
modulates motor output. Whether this involves direct control of movement, or reflects a …
modulates motor output. Whether this involves direct control of movement, or reflects a …
Interpreting the role of the striatum during multiple phases of motor learning
The synaptic pathways in the striatum are central to basal ganglia functions including motor
control, learning and organization, action selection, acquisition of motor skills, cognitive …
control, learning and organization, action selection, acquisition of motor skills, cognitive …
The striatum: where skills and habits meet
AM Graybiel, ST Grafton - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
After more than a century of work concentrating on the motor functions of the basal ganglia,
new ideas have emerged, suggesting that the basal ganglia also have major functions in …
new ideas have emerged, suggesting that the basal ganglia also have major functions in …