Interpretation and use of FRAX in clinical practice

JA Kanis, D Hans, C Cooper, S Baim… - Osteoporosis …, 2011 - Springer
The introduction of the WHO FRAX® algorithms has facilitated the assessment of fracture
risk on the basis of fracture probability. Its use in fracture risk prediction has strengths, but …

A brief history of FRAX

JA Kanis, H Johansson, NC Harvey… - Archives of …, 2018 - Springer
This paper reviews the research programme that went into the development of FRAX® and
its impact in the 10 years since its release in 2008. Introduction Osteoporosis is defined on …

Pitfalls in the external validation of FRAX

JA Kanis, A Oden, H Johansson… - Osteoporosis International, 2012 - Springer
Recent studies have evaluated the performance of FRAX® in independent cohorts. The
interpretation of most is problematic for reasons summarised in this perspective. Introduction …

Update of the fracture risk prediction tool FRAX: a systematic review of potential cohorts and analysis plan

L Vandenput, H Johansson, EV McCloskey… - Osteoporosis …, 2022 - Springer
We describe the collection of cohorts together with the analysis plan for an update of the
fracture risk prediction tool FRAX with respect to current and novel risk factors. The resource …

Fracture prediction and calibration of a Canadian FRAX® tool: a population-based report from CaMos

LA Fraser, L Langsetmo, C Berger, G Ioannidis… - Osteoporosis …, 2011 - Springer
A new Canadian WHO fracture risk assessment (FRAX®) tool to predict 10-year fracture
probability was compared with observed 10-year fracture outcomes in a large Canadian …

Independent clinical validation of a Canadian FRAX tool: fracture prediction and model calibration

WD Leslie, LM Lix, H Johansson, A Oden… - Journal of bone and …, 2010 - academic.oup.com
A FRAX model for Canada was constructed for prediction of osteoporotic and hip fracture
risk using national hip fracture data with and without the use of femoral neck bone mineral …

FRAX and fracture prediction without bone mineral density

JA Kanis, NC Harvey, H Johansson, A Oden… - …, 2015 - Taylor & Francis
The major application of FRAX in osteoporosis is to direct pharmacological interventions to
those at high risk of fracture. Whereas the efficacy of osteoporosis treatment, with the …

The utility and limitations of FRAX: a US perspective

SL Silverman, AD Calderon - Current osteoporosis reports, 2010 - Springer
The FRAX calculator is a major achievement in terms of our understanding of measuring
fracture risk. Along with being an easily accessible web-based tool, it is the only model …

FRAX update

JA Kanis, NC Harvey, H Johansson, A Odén… - Journal of Clinical …, 2017 - Elsevier
The fracture risk assessment tool, FRAX, was released in 2008 and provides country-
specific algorithms for estimating individualized 10-year probability of hip and major …

Joint Official Positions of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX®: Executive Summary of the 2010 …

DB Hans, JA Kanis, S Baim, JP Bilezikian… - Journal of Clinical …, 2011 - Elsevier
The International Society for Clinical Densitometry (ISCD) and the International
Osteoporosis Foundation (IOF) convened the FRAX® Position Development Conference …