Background: Anterior cruciate ligament (ACL) tears often result in knee effusion and an
increased risk for developing knee osteoarthritis (OA) in the long run. The molecular profile …

Background: Anterior cruciate ligament (ACL) tears are associated with posttraumatic
osteoarthritis, but the early biological changes that initiate joint degeneration after this injury …

Objective The purpose of this study was to evaluate changes in the synovial fluid proteome
following acute anterior cruciate ligament (ACL) injury. Design This study represents a …

Purpose: Elevated synovial fluid concentrations of pro-inflammatory cytokines, degradative
enzymes, and cartilage breakdown markers at the time of anterior cruciate ligament (ACL) …

Purpose To establish how synovial fluid biomarker concentrations change in patients after
anterior cruciate ligament (ACL) tears, with and without associated cartilage injury, with …

Surgical transection of the anterior cruciate ligament (ACL) in the porcine model leads to
posttraumatic osteoarthritis if left untreated. However, a recently developed surgical …

Objective To describe the longitudinal patterns of release, and investigate the association
between a set of synovial fluid biomarkers at the acute and chronic stage and the …

Purpose The current investigation evaluated the relationship between the synovial fluid
cytokine microenvironment at the time of isolated anterior cruciate ligament (ACL) …

Objective The pathophysiology of the most common joint disease, osteoarthritis (OA),
remains poorly understood. Since synovial fluid (SF) bathes joint cartilage and synovium, we …

Anterior cruciate ligament (ACL) trauma often occurs in combination with injury to the
articular cartilage of the knee, this can result in earlier radiographic evidence of post …