Background In some countries extracts of the plant Hypericum perforatum L.(popularly
called St. John's wort) are widely used for treating patients with depressive symptoms …

Background Extracts of the plant Hypericum perforatum L.(popularly called St. John's wort)
have been used in folk medicine for a long time for a range of indications including …

Abstract The herbal remedy St John's wort is widely used as an antidepressant but its
efficacy has not been systematically investigated. Meta-analyses and systematic reviews of …

BackgroundExtracts of Hypericum perforatum (St John's wort) are widely used to treat
depression. Evidence for its efficacy has been criticised on methodological grounds. AimsTo …

Highlights•This is the most up-to-date, large-scale meta-analysis of St John's wort.•Studies
published in English, German and Chinese were examined.•27 clinical trials with a total of …

Objective: To investigate if extracts of Hypericum perforatum (St John's wort) are more
effective than placebo in the treatment of depression, are as effective as standard …

Background This systematic review evaluated St. John's wort (SJW) for the treatment of
Major Depressive Disorder (MDD). The objectives of this review are to (1) evaluate the …

Hypericum perforatum is a medicinal plant with established antidepressant properties. The
aim of this meta-analysis was to compare the efficacy and tolerability of this antidepressant …

Background The aim of the current study was to assess the antidepressant efficacy and
safety of Hypericum perforatum (St. John's wort) extract WS® 5570 at doses of 600 mg/day …

Depression is a common condition in the community with a significant impact on affected
individuals, their relatives and society. Many patients with depression do not seek treatment …