[HTML][HTML] The role of the VEGF family in coronary heart disease

Y Zhou, X Zhu, H Cui, J Shi, G Yuan, S Shi… - Frontiers in …, 2021 - frontiersin.org
The vascular endothelial growth factor (VEGF) family, the regulator of blood and lymphatic
vessels, is mostly investigated in the tumor and ophthalmic field. However, the functions it …

[HTML][HTML] The role of the VEGF family in atherosclerosis development and its potential as treatment targets

SA Dabravolski, VA Khotina, AV Omelchenko… - International journal of …, 2022 - mdpi.com
The vascular endothelial growth factor (VEGF) family, the crucial regulator of angiogenesis,
lymphangiogenesis, lipid metabolism and inflammation, is involved in the development of …

[HTML][HTML] VEGF-A in cardiomyocytes and heart diseases

M Braile, S Marcella, L Cristinziano… - International Journal of …, 2020 - mdpi.com
The vascular endothelial growth factor (VEGF), a homodimeric vasoactive glycoprotein, is
the key mediator of angiogenesis. Angiogenesis, the formation of new blood vessels, is …

Signaling pathways induced by vascular endothelial growth factor

B Larrivee, A Karsan - International journal of …, 2000 - spandidos-publications.com
Vasculogenesis and angiogenesis are the mechanisms responsible for the development of
the blood vessels. Angiogenesis refers to the formation of capillaries from pre-existing …

[HTML][HTML] Molecular bases of VEGFR-2-mediated physiological function and pathological role

X Wang, AM Bove, G Simone, B Ma - Frontiers in Cell and …, 2020 - frontiersin.org
The vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) play crucial
roles in vasculogenesis and angiogenesis. Angiogenesis is an important mechanism in …

VEGF‐B‐induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart

R Kivelä, M Bry, MR Robciuc, M Räsänen… - EMBO molecular …, 2014 - embopress.org
Angiogenic growth factors have recently been linked to tissue metabolism. We have used
genetic gain‐and loss‐of function models to elucidate the effects and mechanisms of action …

[HTML][HTML] VEGFR-1 and VEGFR-2: two non-identical twins with a unique physiognomy

N Rahimi - Frontiers in bioscience: a journal and virtual library, 2006 - ncbi.nlm.nih.gov
Angiogenesis involves endothelial cell differentiation, proliferation, migration and cord
formation, which lead to tubulogenesis to form vessels. One group of growth factor receptors …

The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions

H Takahashi, M Shibuya - Clinical science, 2005 - portlandpress.com
The VEGF (vascular endothelial growth factor) family and its receptors are essential
regulators of angiogenesis and vascular permeability. Currently, the VEGF family consists of …

Molecular mechanism of VEGF and its role in pathological angiogenesis

A Ahmad, MI Nawaz - Journal of Cellular Biochemistry, 2022 - Wiley Online Library
Over the last seven decades, a significant scientific contribution took place in the delineation
of the implications of vascular endothelial‐derived growth factor (VEGF) in the processes of …

Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor

I Zachary - American Journal of Physiology-Cell Physiology, 2001 - journals.physiology.org
Vascular endothelial growth factor (VEGF) is essential for angiogenesis in health and
pathophysiology, and it is currently a major focus for drug targeting in the development of …