A trend towards the abandonment of obtaining pure culture isolates in frontline laboratories
is at a crossroads with the ability of public health agencies to perform their basic mandate of …

Traditional pathogen detection methods in public health infectious disease surveillance rely
upon the identification of agents that are already known to be associated with a particular …

High throughput sequencing has been proposed as a one-stop solution for diagnostics and
molecular typing directly from patient samples, allowing timely and appropriate …

Next-generation sequencing (NGS) technologies have become increasingly available for
use in the clinical microbiology diagnostic environment. There are three main applications of …

Metagenomics has become one of the indispensable tools in microbial ecology for the last
few decades, and a new revolution in metagenomic studies is now about to begin, with the …

Since nucleic acids were first extracted directly from the environment and sequenced,
metagenomics has grown to one of the most data-rich and pervasive techniques for …

Advancements in next-generation sequencing technology have dramatically reduced the
cost and increased the ease of microbial whole genome sequencing. This approach is …

The application of sequencing technology is shifting from research to clinical laboratories
owing to rapid technological developments and substantially reduced costs. However …

Diverse microbial communities of bacteria, archaea, viruses and single-celled eukaryotes
have crucial roles in the environment and in human health. However, microbes are …

The study of microorganisms that pervade each and every part of this planet has
encountered many challenges through time such as the discovery of unknown organisms …