The phthalic selenoanhydride decreases rat blood pressure and tension of isolated mesenteric, femoral and renal arteries
P Balis, A Berenyiova, A Misak, M Grman, Z Rostakova… - Molecules, 2023 - mdpi.com
Phthalic selenoanhydride (R-Se) solved in physiological buffer releases various reactive
selenium species including H2Se. It is a potential compound for Se supplementation which …
selenium species including H2Se. It is a potential compound for Se supplementation which …
Evaluation of cardiovascular parameters of a selenium-based antihypertensive using pulsed Doppler ultrasound
JD Overcast, AE Ensley, CJ Buccafusco… - Journal of …, 2001 - journals.lww.com
The pharmacology of selenium is of much interest because selenium deficiency has been
linked to cardiovascular diseases, cancer, and arthritis, and selenoenzymes are critical …
linked to cardiovascular diseases, cancer, and arthritis, and selenoenzymes are critical …
An orally active selenium-based antihypertensive agent with restricted CNS permeability
SW May, L Wang, MM Gill-Woznichak… - … of Pharmacology and …, 1997 - ASPET
We report here the first orally active, selenium-based antihypertensive agent, and we
demonstrate its restricted CNS permeability using inductively coupled plasma/mass …
demonstrate its restricted CNS permeability using inductively coupled plasma/mass …
Selenium and vascular health
AA Sneddon - Pure and Applied Chemistry, 2011 - degruyter.com
Selenium (Se) is an important dietary micronutrient required for sustaining optimal health.
Se is incorporated into proteins, many of which are antioxidants that protect the body against …
Se is incorporated into proteins, many of which are antioxidants that protect the body against …
Products of Selenite/Thiols Interaction Have Reducing Properties, Cleave Plasmid DNA and Decrease Rat Blood Pressure and Tension of Rat Mesenteric Artery
M Grman, P Balis, A Berenyiova… - … Trace Element Research, 2024 - Springer
Selenium compounds exert their antioxidant activity mostly when the selenium atom is
incorporated into selenoproteins. In our work, we tested the possibility that selenite itself …
incorporated into selenoproteins. In our work, we tested the possibility that selenite itself …
Effects of a novel selenium substituted-sugar (1, 4-anhydro-4-seleno-d-talitol, SeTal) on human coronary artery cell lines and mouse aortic rings
Chronic low-grade inflammation and oxidative damage are strongly associated with
pathologies including cardiovascular disease. As a consequence, there is considerable …
pathologies including cardiovascular disease. As a consequence, there is considerable …
Long-term excessive selenium supplementation induces hypertension in rats
D Grotto, MFH Carneiro, MM De Castro… - Biological trace element …, 2018 - Springer
Selenium (Se) is an essential trace element involved in several biological pathways,
naturally found in rocks, soils, and food. Even though the daily requirement of Se is achieved …
naturally found in rocks, soils, and food. Even though the daily requirement of Se is achieved …
Enhancement of endothelium dependent relaxation in the rat aortic ring by selenium supplement
X Lu, SY Liu, RYK Man - Cardiovascular research, 1994 - academic.oup.com
Objective: The aim was to examine the effect of selenium supplement on endothelium
dependent relaxation in rat aortic rings. Methods: Rats were supplemented with selenium for …
dependent relaxation in rat aortic rings. Methods: Rats were supplemented with selenium for …
Selenium-based antihypertensives: rationale and potential
SW May, SH Pollock - Drugs, 1998 - Springer
Selenium, long recognised as an important 'dietary antioxidant', is now known to be an
essential component of the active sites of a number of enzymes, including the glutathione …
essential component of the active sites of a number of enzymes, including the glutathione …
Selenium restores defective beta-adrenergic receptor response of thoracic aorta in diabetic rats
EN Zeydanli, A Bilginoglu, E Tanriverdi… - Molecular and cellular …, 2010 - Springer
Increased oxidative stress is one of the basic contributors to the development of the
cardiovascular complications in diabetes. Both endothelial and vascular smooth muscle cell …
cardiovascular complications in diabetes. Both endothelial and vascular smooth muscle cell …