[HTML][HTML] Caprylic acid suppresses inflammation via TLR4/NF-κB signaling and improves atherosclerosis in ApoE-deficient mice

X Zhang, C Xue, Q Xu, Y Zhang, H Li, F Li, Y Liu… - Nutrition & …, 2019 - Springer
Background As reported previously by our group, medium-chain triglycerides can ameliorate
atherosclerosis. Given that TLR4 is closely related to atherosclerosis, we hypothesized …

Caprylic acid improves lipid metabolism, suppresses the inflammatory response and activates the ABCA1/p-JAK2/p-STAT3 signaling pathway in C57BL/6J mice and …

XS Zhang, P Zhang, YH Liu, XU Qing, Y Zhang… - Biomedical and …, 2022 - Elsevier
Objective This study aimed to investigate the effects of caprylic acid (C8: 0) on lipid
metabolism and inflammation, and examine the mechanisms underlying these effects in …

[HTML][HTML] Probiotic mixture VSL#3 reduce high fat diet induced vascular inflammation and atherosclerosis in ApoE−/− mice

YK Chan, H El-Nezami, Y Chen, K Kinnunen… - Amb Express, 2016 - Springer
Atherosclerosis results from chronic inflammation potentially caused by translocation of
bacterial components from the oro-gastrointestinal tract to circulation. Specific probiotics …

[HTML][HTML] Palmitoleic acid ameliorates palmitic acid-induced proinflammation in J774A. 1 macrophages via TLR4-dependent and TNF-α-independent signallings

YW Tsai, CH Lu, RCA Chang, YP Hsu, LT Ho… - … and Essential Fatty …, 2021 - Elsevier
Adipose tissue resident macrophages play an important role in the regulation of the
inflammatory response. Monounsaturated fatty acids assist in the prevention of …

Cinnamaldehyde attenuates atherosclerosis via targeting the IκB/NF-κB signaling pathway in high fat diet-induced ApoE−/− mice

W Li, W Zhi, J Zhao, W Li, L Zang, F Liu, X Niu - Food & Function, 2019 - pubs.rsc.org
Cinnamaldehyde is a flavor isolated from the bark of Cinnamomum cassia Presl and exerts
anti-inflammation effects in various diseases. In our study, we investigated the protective …

[HTML][HTML] Amygdalin attenuates atherosclerosis and plays an anti-inflammatory role in ApoE knock-out mice and bone marrow-derived macrophages

Y Wang, Q Jia, Y Zhang, J Wei, P Liu - Frontiers in Pharmacology, 2020 - frontiersin.org
Amygdalin, the main component of Prunus persica (L.) Stokes, has been used to treat
atherosclerosis in mouse model due to its anti-inflammatory role. However, the underlying …

Salvianolic acid B attenuates the inflammatory response in atherosclerosis by regulating MAPKs/NF-κB signaling pathways in LDLR-/-mice and RAW264. 7 cells

Y Zhang, X Feng, M Du, J Ding… - International Journal of …, 2022 - journals.sagepub.com
Objectives: Salvianolic acid B (Sal B) is the main effective water-soluble component of
Salvia miltiorrhiza. In this study, the anti-inflammatory effect of Sal B was explored in high-fat …

[HTML][HTML] Fish oil rich diet in comparison to saturated fat rich diet offered protection against lipopolysaccharide-induced inflammation and insulin resistance in mice

M Vijay-Kumar, SM Vanegas, N Patel, JD Aitken… - Nutrition & …, 2011 - Springer
Abstract Background and Objective Systemic chronic inflammation is linked to metabolic
syndrome, type-2 diabetes, and heart disease. Lipopolysaccharide (LPS), a Gram negative …

Dietary palmitoleic acid attenuates atherosclerosis progression and hyperlipidemia in low‐density lipoprotein receptor‐deficient mice

ZH Yang, M Pryor, A Noguchi… - Molecular nutrition & …, 2019 - Wiley Online Library
Scope Palmitoleic acid (palmitoleate; C16: 1 n‐7), an omega‐7 monounsaturated fatty acid
(MUFA) found in plants and marine sources, has been shown to favorably modulate lipid …

[HTML][HTML] Short-chain fatty acids weaken ox-LDL-induced cell inflammatory injury by inhibiting the NLRP3/Caspase-1 pathway and affecting cellular metabolism in THP …

C Yi, W Sun, L Ding, M Yan, C Sun, C Qiu, D Wang… - Molecules, 2022 - mdpi.com
Short-chain fatty acids (SCFAs) are important anti-inflammatory metabolites of intestinal
flora. Oxidized low-density lipoprotein (ox-LDL)-induced macrophage activation is critical for …