Selective modulation of cortical state during spatial attention

TA Engel, NA Steinmetz, MA Gieselmann, A Thiele… - Science, 2016 - science.org
Neocortical activity is permeated with endogenously generated fluctuations, but how these
dynamics affect goal-directed behavior remains a mystery. We found that ensemble neural …

Top-down coordination of local cortical state during selective attention

J van Kempen, MA Gieselmann, M Boyd, NA Steinmetz… - Neuron, 2021 - cell.com
Spontaneous fluctuations in cortical excitability influence sensory processing and behavior.
These fluctuations, long thought to reflect global changes in cortical state, were recently …

Learning is shaped by abrupt changes in neural engagement

JA Hennig, ER Oby, MD Golub, LA Bahureksa… - Nature …, 2021 - nature.com
Internal states such as arousal, attention and motivation modulate brain-wide neural activity,
but how these processes interact with learning is not well understood. During learning, the …

Intrinsic timescales in the visual cortex change with selective attention and reflect spatial connectivity

R Zeraati, YL Shi, NA Steinmetz… - Nature …, 2023 - nature.com
Intrinsic timescales characterize dynamics of endogenous fluctuations in neural activity.
Variation of intrinsic timescales across the neocortex reflects functional specialization of …

Spontaneous behaviors drive multidimensional, brainwide activity

C Stringer, M Pachitariu, N Steinmetz, CB Reddy… - Science, 2019 - science.org
INTRODUCTION In the absence of sensory inputs, the brain produces structured patterns of
activity, which can be as large as or larger than sensory-driven activity. Ongoing activity …

Neural mechanisms of visual attention: how top-down feedback highlights relevant locations

YB Saalmann, IN Pigarev, TR Vidyasagar - Science, 2007 - science.org
Attention helps us process potentially important objects by selectively increasing the activity
of sensory neurons that represent the relevant locations and features of our environment …

Rapid fluctuations in functional connectivity of cortical networks encode spontaneous behavior

H Benisty, D Barson, AH Moberly, S Lohani… - Nature …, 2024 - nature.com
Experimental work across species has demonstrated that spontaneously generated
behaviors are robustly coupled to variations in neural activity within the cerebral cortex …

Entrainment of neuronal oscillations as a mechanism of attentional selection

P Lakatos, G Karmos, AD Mehta, I Ulbert… - science, 2008 - science.org
Whereas gamma-band neuronal oscillations clearly appear integral to visual attention, the
role of lower-frequency oscillations is still being debated. Mounting evidence indicates that a …

Spontaneous fluctuations in neural responses to heartbeats predict visual detection

HD Park, S Correia, A Ducorps, C Tallon-Baudry - Nature neuroscience, 2014 - nature.com
Spontaneous fluctuations of ongoing neural activity substantially affect sensory and
cognitive performance. Because bodily signals are constantly relayed up to the neocortex …

Selective attention from voluntary control of neurons in prefrontal cortex

RJ Schafer, T Moore - Science, 2011 - science.org
Animals can learn to voluntarily control neuronal activity within various brain areas through
operant conditioning, but the relevance of that control to cognitive functions is unknown. We …