Alzheimers disease (AD) is a multifactorial disease for which therapeutic efficacy should
benefit from a multi-target approach. Thus, we evaluated a combined chronic treatment with …

Alzheimer's disease (AD) is the major form of dementia prevalent in older adults and with a
high incidence in females. Identification of early biomarkers is essential for preventive …

Alzheimer's disease (AD) is characterized by extracellular amyloid plaques composed of β-
amyloid (Aβ) and intracellular neurofibrillary tangles containing hyperphosphorylated tau …

The process of aging is defined by the breakdown of critical maintenance pathways leading
to an accumulation of damage and its associated phenotypes. Aging affects many systems …

Abstract β-Amyloid oligomers (AβOs) and neuroinflammation are 2 main culprits to
counteract in Alzheimer's disease (AD). Doxycycline (DOXY) is a second generation …

A double blind, placebo-controlled phase II study revealed that the antihistamine,
Dimebon®(dimebolin, latrepirdine) improved cognition in Alzheimer disease (AD) patients …

Memory loss is the most common occurrence of dementia in the elderly population.
Evidence shows 1, 2-Diacetylbenzene (DAB) can exacerbate cerebral dysfunction. The …

J. Neurochem.(2011) 10.1111/j. 1471‐4159.2011. 07514. x Abstract Various environmental
factors are known to influence the onset and progression of Alzheimer's disease (AD) …

Alzheimer's disease (AD) is accompanied by hippocampal neuronal loss and abnormal
neurogenesis, both of which probably contributing to AD-related cognitive deficits. Mounting …

Oxidative stress is known to play a prominent role in the onset and early stage progression
of Alzheimer's disease (AD). For example, protein oxidation and lipid peroxidation levels are …