[HTML][HTML] Integrating circulating-free DNA (cfDNA) analysis into clinical practice: opportunities and challenges
M Garcia-Pardo, M Makarem, JJN Li, D Kelly… - British Journal of …, 2022 - nature.com
In the current era of precision medicine, the identification of genomic alterations has
revolutionised the management of patients with solid tumours. Recent advances in the …
revolutionised the management of patients with solid tumours. Recent advances in the …
[HTML][HTML] Making the rounds: exploring the role of circulating tumor DNA (ctDNA) in non-small cell lung cancer
MD Shields, K Chen, G Dutcher, I Patel… - International journal of …, 2022 - mdpi.com
Advancements in the clinical practice of non-small cell lung cancer (NSCLC) are shifting
treatment paradigms towards increasingly personalized approaches. Liquid biopsies using …
treatment paradigms towards increasingly personalized approaches. Liquid biopsies using …
[HTML][HTML] Clinical relevance of blood-based ctDNA analysis: mutation detection and beyond
Cell-free DNA (cfDNA) derived from tumours is present in the plasma of cancer patients. The
majority of currently available studies on the use of this circulating tumour DNA (ctDNA) deal …
majority of currently available studies on the use of this circulating tumour DNA (ctDNA) deal …
Liquid biopsies come of age: towards implementation of circulating tumour DNA
Improvements in genomic and molecular methods are expanding the range of potential
applications for circulating tumour DNA (ctDNA), both in a research setting and as a'liquid …
applications for circulating tumour DNA (ctDNA), both in a research setting and as a'liquid …
Review of the clinical applications and technological advances of circulating tumor DNA in cancer monitoring
Y Chang, B Tolani, X Nie, X Zhi, M Hu… - Therapeutics and clinical …, 2017 - Taylor & Francis
Circulating cell-free DNA (cfDNA) released by tumor cells, termed ctDNA, closely reflects the
heterogeneity of primary cancers and their metastases. As a noninvasive, real-time …
heterogeneity of primary cancers and their metastases. As a noninvasive, real-time …
[HTML][HTML] Circulating cell free tumor DNA detection as a routine tool for lung cancer patient management
JA Vendrell, FT Mau-Them, B Béganton… - International journal of …, 2017 - mdpi.com
Circulating tumoral DNA (ctDNA), commonly named “liquid biopsy”, has emerged as a new
promising noninvasive tool to detect biomarker in several cancers including lung cancer …
promising noninvasive tool to detect biomarker in several cancers including lung cancer …
Advances in circulating tumor DNA analysis
The analysis of cell-free circulating tumor DNA (ctDNA) is a very promising tool and might
revolutionize cancer care with respect to early detection, identification of minimal residual …
revolutionize cancer care with respect to early detection, identification of minimal residual …
[HTML][HTML] Leveraging the fragment length of circulating tumour DNA to improve molecular profiling of solid tumour malignancies with next-generation sequencing: a …
HR Underhill - Molecular diagnosis & therapy, 2021 - Springer
Circulating cell-free DNA (ccfDNA) has emerged as a promising diagnostic tool in oncology.
Identification of tumour-derived ccfDNA (ie circulating tumour DNA [ctDNA]) provides non …
Identification of tumour-derived ccfDNA (ie circulating tumour DNA [ctDNA]) provides non …
[HTML][HTML] Cell-free circulating tumour DNA as a liquid biopsy in breast cancer
L De Mattos-Arruda, C Caldas - Molecular oncology, 2016 - Elsevier
Recent developments in massively parallel sequencing and digital genomic techniques
support the clinical validity of cell-free circulating tumour DNA (ctDNA) as a 'liquid biopsy'in …
support the clinical validity of cell-free circulating tumour DNA (ctDNA) as a 'liquid biopsy'in …
Circulating cell-free DNA for non-invasive cancer management
CM Stewart, DWY Tsui - Cancer Genetics, 2018 - Elsevier
Highlights•Cell-free nucleic acids in body fluids contain tumour fragments that can be
profiled for prognostic and diagnostic information for the management of cancer.•cfDNA …
profiled for prognostic and diagnostic information for the management of cancer.•cfDNA …