Although the molecular pathways leading to the progressive deterioration of stored red
blood cells (RBC storage lesion) and the clinical relevance of storage‐induced changes …

Red blood cell storage lesion (RSL) is a multifaceted biological phenomenon. It refers to
deterioration in RBC quality that is characterized by lethal and sub-lethal, reversible and …

BACKGROUND Previous studies have shown that baseline hematologic characteristics
concerning or influencing red blood cell (RBC) properties might affect storage lesion …

Over the last decade, the introduction of omics technologies–especially high-throughput
genomics and metabolomics–has contributed significantly to our understanding of the role of …

Background Several factors contribute to the manifestation of red blood cell (RBC) storage
lesions, with one of the most interesting being the “donor variation effect”. Since many …

The collection and storage of red blood cells (RBCs) is a logistical necessity to provide
sufficient blood products. However, RBC storage is an unnatural state, resulting in …

Red blood cell (RBC) storage in the blood bank is characterized by the progressive loss of
metabolic regulation, a phenomenon that targets energy and antioxidant metabolism; While …

Quality and safety of red blood cell (RBC) components is managed by screening of donors
and strict regulatory controls of blood collection, processing and storage procedures …

Background R ed blood cell (RBC) storage lesions have been suggested as contributing
factors to suboptimal clinical outcomes. While undesirable effects of storage are well …

BACKGROUND Genetic determinants may underlie the susceptibility of red blood cells
(RBCs) to hemolyze in vivo and during routine storage. This study characterized the …