The spread of Enterobacteriaceae, primarily Klebsiella pneumoniae, producing KPC, VIM,
IMP, and NDM carbapenemases, is causing an unprecedented public health crisis …

Carbapenemase-producing Enterobacteriaceae (CPE) were almost nonexistent up to the
1990s, but are today encountered routinely in hospitals and other healthcare facilities in …

The wide dissemination of carbapenemase-producing Gram-negatives (CPGNs), including
enterobacterial species and non-fermenters, has caused a public health crisis of global …

Infections caused by carbapenemase-producing Klebsiella pneumoniae (CPKP) are
increasing in frequency worldwide. CPKP isolates exhibit extensive drug resistance …

Dissemination of carbapenemase-producing Klebsiella pneumoniae (CP-Kp) has caused a
public health crisis that can be paralleled with that caused by the spread of MRSA. CP-Kps …

Since the discovery of penicillin 80 years ago, gram‐negative bacteria have become
proficient at evading the lethal activity of β‐lactam antibiotics, principally through the …

Increasing carbapenem resistance in Enterobacterales poses a threat to public health. In
recent decades, this increase in carbapenem resistance has been caused by the global …

Background Carbapenem resistance is defined as in vitro non-susceptibility to any
carbapenem and/or documented production of a carbapenemase. This feature has rapidly …

The prevalence of carbapenem‐resistant Gram‐negative bacilli is on the rise worldwide,
posing a major public health threat. Previously, this was mostly a problem in Pseudomonas …

Carbapenemases increasingly have been reported in Enterobacteriaceae in the past 10
years. Klebsiella pneumoniae carbapenemases have been reported in the United States …