Mass spectrometric imaging for biomedical tissue analysis

K Chughtai, RMA Heeren - Chemical reviews, 2010 - ACS Publications
A mass spectrometer is described as the smallest weighing scale ever used in the world. 1
Mass spectrometry (MS) is a unique technique that has an interdisciplinary nature, which …

Imaging mass spectrometry: hype or hope?

RMA Heeren, DF Smith, J Stauber… - Journal of the American …, 2009 - Springer
Imaging mass spectrometry is currently receiving a significant amount of attention in the
mass spectrometric community. It offers the potential of direct examination of biomolecular …

Mass spectrometry imaging of biomolecular information

B Spengler - Analytical chemistry, 2015 - ACS Publications
Mass spectrometry imaging (MSI) has gone through a significant change over the last 3
years, the time span of this review. The predominant mass spectrometric method in …

Imaging mass spectrometry of thin tissue sections: a decade of collective efforts

P Chaurand - Journal of proteomics, 2012 - Elsevier
Imaging mass spectrometry (MS) allows to monitor the spatial distribution and abundance of
endogenous and administered compounds present within tissue specimens. Several …

Molecular mass spectrometry imaging in biomedical and life science research

J Pól, M Strohalm, V Havlíček, M Volný - Histochemistry and cell biology, 2010 - Springer
This review describes the current state of mass spectrometry imaging (MSI) in life sciences.
A brief overview of mass spectrometry principles is presented followed by a thorough …

Molecular imaging of thin mammalian tissue sections by mass spectrometry

P Chaurand, DS Cornett, RM Caprioli - Current opinion in biotechnology, 2006 - Elsevier
Imaging of tissue sections by mass spectrometry provides a detailed molecular picture
containing information on both the abundance and distribution of many constituent …

Current state and future challenges of mass spectrometry imaging for clinical research

RD Addie, B Balluff, JVMG Bovée, H Morreau… - 2015 - ACS Publications
The ability of mass spectrometry imaging (MSI) to localize panels of biomolecules in tissues,
without prior knowledge of their presence and in a label-free manner, has led to a rapid and …

Emerging technologies in mass spectrometry imaging

JH Jungmann, RMA Heeren - Journal of proteomics, 2012 - Elsevier
Mass spectrometry imaging (MSI) as an analytical tool for bio-molecular and bio-medical
research targets accurate compound localization and identification. In terms of dedicated …

Imaging mass spectrometry: instrumentation, applications, and combination with other visualization techniques

A Bodzon‐Kulakowska, P Suder - Mass spectrometry reviews, 2016 - Wiley Online Library
Imaging Mass Spectrometry (IMS) is strengthening its position as a valuable analytical tool. It
has unique ability to identify structures and to unravel molecular changes that occur in the …

[PDF][PDF] Imaging with mass spectrometry

ML Pacholski, N Winograd - Chemical reviews, 1999 - academia.edu
Imaging mass spectrometry (MS) has created new fundamental research opportunities in
many fields because of its unique ability to acquire molecule-and element-specific pictures …